GPVI binds Fyn and Lyn

Stable Identifier
R-HSA-432295
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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GPVI binds Fyn and Lyn
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Fyn and Lyn constitutively associate with GPVI-Fc epsilon R1 gamma in platelets. The proline-rich region of GPVI is required for this interaction.

Literature References
PubMed ID Title Journal Year
11943772 Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling

Suzuki-Inoue, K, Tulasne, D, Shen, Y, Bori-Sanz, T, Inoue, O, Jung, SM, Moroi, M, Andrews, RK, Berndt, MC, Watson, SP

J Biol Chem 2002
Participants
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Orthologous Events
GPVI binds Fyn and Lyn (Bos taurus)
GPVI binds Fyn and Lyn (Canis familiaris)
GPVI binds Fyn and Lyn (Mus musculus)
GPVI binds Fyn and Lyn (Rattus norvegicus)
GPVI binds Fyn and Lyn (Sus scrofa)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Harper, MT  (2009-11-02)
Created
Jupe, S  (2009-08-13)