Reactome | GPVI binds Fyn and Lyn

GPVI binds Fyn and Lyn

Stable Identifier

R-HSA-432295

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

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Fyn and Lyn constitutively associate with GPVI-Fc epsilon R1 gamma in platelets. The proline-rich region of GPVI is required for this interaction.

Literature References

PubMed ID	Title	Journal	Year
11943772	Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling Suzuki-Inoue, K, Moroi, M, Bori-Sanz, T, Inoue, O, Berndt, MC, Watson, SP, Tulasne, D, Andrews, RK, Jung, SM, Shen, Y	J Biol Chem	2002