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AQP4 [plasma membrane]
Stable Identifier
R-HSA-431733
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Aquaporin-4, AQP4_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Passive transport by Aquaporins (Homo sapiens)
Aquaporins passively transport water into cells (Homo sapiens)
AQP0,1,2,3,4,5,7,8,9,10,11,12A [plasma membrane] (Homo sapiens)
AQP4 tetramer [plasma membrane] (Homo sapiens)
AQP4 [plasma membrane] (Homo sapiens)
Aquaporins passively transport water out of cells (Homo sapiens)
AQP0,1,2,3,4,5,7,8,9,10,11,12A [plasma membrane] (Homo sapiens)
AQP4 tetramer [plasma membrane] (Homo sapiens)
AQP4 [plasma membrane] (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
Aquaporin-4 passively transports water out of cell (Homo sapiens)
AQP4 [plasma membrane] (Homo sapiens)
AQP4 tetramer [plasma membrane] (Homo sapiens)
AQP4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55087 AQP4
Gene Names
AQP4
Chain
chain:1-323
Reference Genes
BioGPS Gene:361 AQP4
COSMIC (genes):AQP4 AQP4
CTD Gene:361 AQP4
dbSNP Gene:361 AQP4
ENSEMBL:ENSG00000171885.18 AQP4
HGNC:637 AQP4
KEGG Gene (Homo sapiens):361 AQP4
Monarch:361 AQP4
NCBI Gene:361 AQP4
OMIM:600308 AQP4
UCSC:P55087 AQP4
Reference Transcript
RefSeq:NM_004028.4 AQP4
RefSeq:NM_001650.5 AQP4
Other Identifiers
0002970040
0004150088
0004150619
11722619_a_at
11722620_a_at
11722621_a_at
11752685_a_at
11752686_x_at
16854414
210066_PM_s_at
210066_s_at
210067_PM_at
210067_at
210068_PM_s_at
210068_s_at
210906_PM_x_at
210906_x_at
226228_PM_at
226228_at
361
3802398
3802399
3802400
3802401
3802402
3802403
3802404
3802406
3802407
3802409
3802410
3802411
3802412
3802414
3802415
40793_s_at
8022655
A_23_P107565
A_24_P202522
A_33_P3420757
D63412_at
GE57270
GE596123
GO:0002376
GO:0003014
GO:0003091
GO:0005215
GO:0005515
GO:0005576
GO:0005622
GO:0005737
GO:0005768
GO:0005886
GO:0005887
GO:0006833
GO:0007018
GO:0007155
GO:0007565
GO:0009314
GO:0009897
GO:0009925
GO:0009992
GO:0010008
GO:0010574
GO:0015250
GO:0015267
GO:0015670
GO:0016020
GO:0016021
GO:0016323
GO:0022414
GO:0030104
GO:0030315
GO:0031253
GO:0031410
GO:0032691
GO:0032715
GO:0032991
GO:0042383
GO:0042538
GO:0042802
GO:0042995
GO:0043226
GO:0050877
GO:0050891
GO:0051289
GO:0051384
GO:0055085
GO:0060354
GO:0065003
GO:0071333
GO:0071346
GO:0071347
GO:0071354
GO:0071392
GO:0090660
GO:0097450
GO:0098542
GO:0098609
HMNXSV003003919
Hs.315369.0.S1_3p_at
ILMN_1676649
ILMN_1747683
PH_hs_0032638
TC18000429.hg
U34844_at
g1072054_3p_a_at
g1236245_3p_at
g1680707_3p_a_at
Participates
as a component of
AQP4 tetramer [plasma membrane] (Homo sapiens)
Inferred To
Drip [plasma membrane]
(Drosophila melanogaster)
Eglp2 [plasma membrane]
(Drosophila melanogaster)
aqpA [plasma membrane]
(Dictyostelium discoideum)
wacA [plasma membrane]
(Dictyostelium discoideum)
Aqp4 [plasma membrane]
(Mus musculus)
Aqp4 [plasma membrane]
(Rattus norvegicus)
AQP4 [plasma membrane]
(Bos taurus)
AQP4 [plasma membrane]
(Canis familiaris)
AQP4 [plasma membrane]
(Danio rerio)
AQP4 [plasma membrane]
(Dictyostelium discoideum)
AQP4 [plasma membrane]
(Gallus gallus)
AQP4 [plasma membrane]
(Plasmodium falciparum)
AQP4 [plasma membrane]
(Sus scrofa)
Homologues of AQP4 [plasma membrane]
(Dictyostelium discoideum)
Homologues of AQP4 [plasma membrane]
(Drosophila melanogaster)
Prip [plasma membrane]
(Drosophila melanogaster)
aqp4 [plasma membrane]
(Xenopus tropicalis)
bib [plasma membrane]
(Drosophila melanogaster)
Eglp3 [plasma membrane]
(Drosophila melanogaster)
Eglp4 [plasma membrane]
(Drosophila melanogaster)
Eglp1 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001641.1
,
NP_004019.1
Guide to Pharmacology - Targets
691
OpenTargets
ENSG00000171885
GeneCards
P55087
HPA
ENSG00000171885-AQP4
ZINC target
P55087
Ensembl
ENST00000581374
,
ENSP00000462597
,
ENSG00000171885
,
ENSP00000500720
,
ENSP00000372654
,
ENST00000672188
,
ENST00000383168
,
ENST00000440832
,
ENSP00000393121
PRO
P55087
Pharos - Targets
P55087
HMDB Protein
HMDBP10783
PDB
3GD8
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