Mig-2 recruits Migfilin to the cell-ECM adhesions

Stable Identifier
R-HSA-430341
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Mig-2 recruits Migfilin to the cell-ECM adhesions
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Migfilin functions in cell shape modulation regulating filamin-mediated cross-linking and stabilization of actin filaments. Migfilin is recruited to cell–Extra Cellular Matrix adhesion sites in a variety of fibroblasts, epithelial, and endothelial cells by interaction with Mig-2 (Tu et al., 2003).
Literature References
PubMed ID Title Journal Year
12679033 Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

Shi, X, Tu, Y, Chen, K, Wu, C, Wu, S

Cell 2003
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Orthologous Events
Mig-2 recruits Migfilin to the cell-ECM adhesions (Bos taurus)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Caenorhabditis elegans)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Canis familiaris)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Danio rerio)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Drosophila melanogaster)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Gallus gallus)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Mus musculus)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Rattus norvegicus)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Sus scrofa)
Mig-2 recruits Migfilin to the cell-ECM adhesions (Xenopus tropicalis)
Authored
Matthews, L  (2009-10-12)
Reviewed
Wu, C  (2009-11-12)
Created
Matthews, L  (2009-08-06)
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