Rsu-1 interacts with Pinch1

Stable Identifier
R-HSA-430311
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The Ras suppressor, Rsu-1, interacts with the LIM 5 domain of PINCH1 (but not PINCH2) and may inhibit cell migration by stabilizing the Pinch-ILK-parvin adhesion complex (Dougherty et al., 2008; Kadrmas et al., 2004).

Literature References
PubMed ID Title Journal Year
18436335 The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells

Dougherty, GW, Jose, C, Gimona, M, Cutler, ML

Eur J Cell Biol 2008
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created