Rsu-1 interacts with Pinch1

Stable Identifier
R-HSA-430311
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Rsu-1 interacts with Pinch1
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The Ras suppressor, Rsu-1, interacts with the LIM 5 domain of PINCH1 (but not PINCH2) and may inhibit cell migration by stabilizing the Pinch-ILK-parvin adhesion complex (Dougherty et al., 2008; Kadrmas et al., 2004).
Literature References
PubMed ID Title Journal Year
18436335 The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells

Gimona, M, Jose, C, Dougherty, GW, Cutler, ML

Eur J Cell Biol 2008
Participants
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Output
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Orthologous Events
Rsu-1 interacts with Pinch1 (Caenorhabditis elegans)
Rsu-1 interacts with Pinch1 (Canis familiaris)
Rsu-1 interacts with Pinch1 (Dictyostelium discoideum)
Rsu-1 interacts with Pinch1 (Drosophila melanogaster)
Rsu-1 interacts with Pinch1 (Gallus gallus)
Rsu-1 interacts with Pinch1 (Mus musculus)
Rsu-1 interacts with Pinch1 (Rattus norvegicus)
Rsu-1 interacts with Pinch1 (Sus scrofa)
Authored
Matthews, L  (2009-10-12)
Reviewed
Wu, C  (2009-11-12)
Created
Matthews, L  (2009-08-06)
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