Rsu-1 interacts with Pinch1

Stable Identifier
R-HSA-430311
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Rsu-1 interacts with Pinch1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The Ras suppressor, Rsu-1, interacts with the LIM 5 domain of PINCH1 (but not PINCH2) and may inhibit cell migration by stabilizing the Pinch-ILK-parvin adhesion complex (Dougherty et al., 2008; Kadrmas et al., 2004).

Literature References
PubMed ID Title Journal Year
18436335 The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells

Dougherty, GW, Jose, C, Gimona, M, Cutler, ML

Eur J Cell Biol 2008
Participants
Input
Output
Participates
as an event of
Orthologous Events
Rsu-1 interacts with Pinch1 (Caenorhabditis elegans)
Rsu-1 interacts with Pinch1 (Canis familiaris)
Rsu-1 interacts with Pinch1 (Danio rerio)
Rsu-1 interacts with Pinch1 (Drosophila melanogaster)
Rsu-1 interacts with Pinch1 (Gallus gallus)
Rsu-1 interacts with Pinch1 (Mus musculus)
Rsu-1 interacts with Pinch1 (Rattus norvegicus)
Rsu-1 interacts with Pinch1 (Sus scrofa)
Authored
Matthews, L  (2009-10-12)
Reviewed
Wu, C  (2009-11-12)
Created
Matthews, L  (2009-08-06)
Cite Us!