PARVB interacts with the actin cross-linking protein Alpha-actinin (Yamaji et al. 2004). The ILK-PARVB complex may serve as an integrin-anchoring site for alpha-actinin and thereby mediate integrin signaling to alpha-actinin, which has been shown to play an important role in actin polymerization at focal adhesions (Yamaji et al., 2004).
Fujisawa, S, Kanamori, H, Ohno, S, Takasaki, H, Yamaji, S, Ishigatsubo, Y, Takabayashi, M, Yoshimi, R, Mishima, W, Fujimaki, K, Suzuki, A
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