Reactome | FBLIM1 [cytosol]

FBLIM1 [cytosol]

Stable Identifier

R-HSA-430301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Migfilin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WUP2 FBLIM1

Gene Names

FBLIM1, FBLP1

Chain

chain:1-373

Reference Genes

BioGPS Gene:54751 FBLIM1

COSMIC (genes):FBLIM1 FBLIM1

CTD Gene:54751 FBLIM1

dbSNP Gene:54751 FBLIM1

ENSEMBL:ENSG00000162458 FBLIM1

ENSEMBL_homo_sapiens_GENE:ENSG00000162458 FBLIM1

HGNC:24686 FBLIM1

KEGG Gene (Homo sapiens):54751 FBLIM1

Monarch:54751 FBLIM1

NCBI Gene:54751 FBLIM1

OMIM:607747 FBLIM1

UCSC:Q8WUP2 FBLIM1

Reference Transcript

Other Identifiers

0005080273

11718954_a_at

11718955_a_at

11742131_x_at

11747408_x_at

1554795_a_at

1555480_a_at

1555483_x_at

16659746

225258_at

2322037

2322038

2322040

2322044

2322046

2322047

2322048

2322049

2322050

2322051

2322052

2322053

2322057

2322060

2322061

2322062

25287

2K9U

2W0P

44793_s_at

4P3W

54751

72750

7898263

A_14_P109162

A_23_P23457

A_23_P337934

A_24_P94222

AAH19895

AAO15549

AAO49012

AF459643

AK027444

AK055259

AL133035

AL450998

AY180161

BAB55115

BAG51492

BC019895

CAB61365

CCDS163

CCDS30609

CCDS44064

D6R9I4

D6R9V9

D6RA19

D6RAI6

E7EN81

E7EPI5

E7EWE8

ENSG00000162458

ENSP00000364920

ENSP00000364921

ENSP00000364926

ENSP00000416387

ENST00000332305

ENST00000375766

ENST00000375771

ENST00000441801

EntrezGene:54751

FBLIM1

FBLIM1-201

FBLIM1-202

FBLIM1-203

FBLIM1-206

GE56583

GO:0000902

GO:0001650

GO:0001725

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0005856

GO:0005925

GO:0007155

GO:0008092

GO:0008150

GO:0008360

GO:0022607

GO:0030054

GO:0031005

GO:0033623

GO:0034329

GO:0034330

GO:0043167

GO:0043226

GO:0046872

GO:0048856

GO:0065003

GO:0098609

HGNC:24686

HPA025287

HPA072750

Hs.8728.0.S1_3p_at

Hs2.8728.1.A1_3p_s_at

Hs2.8728.2.A1_3p_a_at

Hs2.8728.2.A1_3p_x_at

ILMN_1671754

ILMN_1691249

ILMN_1799471

ILMN_2353143

IPR001781

MIM:607747

NM_001024215

NM_001024216

NM_001350151

NM_017556

NP_001019386

NP_001019387

NP_001337080

NP_060026

PF00412

PH_hs_0000920

SM00132

TC01000197.hg

uc001axd.2

uc001axe.2

uc001axg.2

uc001axi.2

UPI000013E169

UPI000013F27B

UPI0000520D52

XM_005245900

XM_005245901

XM_005245902

XM_005245903

XM_006710704

XM_006710705

XM_011541616

XM_011541617

XM_011541618

XM_017001519

XM_017001520

XM_017001521

XM_017001523

XM_017001524

XM_017001525

XM_017001526

XM_024447751

XP_005245957

XP_005245958

XP_005245959

XP_005245960

XP_006710767

XP_006710768

XP_011539918

XP_011539919

XP_011539920

XP_016857008

XP_016857009

XP_016857010

XP_016857012

XP_016857013

XP_016857014

XP_016857015

XP_024303519

Participant Of

hasComponent

input

Inferred To

FBLIM1 [cytosol] (Bos taurus)

FBLIM1 [cytosol] (Caenorhabditis elegans)

FBLIM1 [cytosol] (Canis familiaris)

FBLIM1 [cytosol] (Danio rerio)

FBLIM1 [cytosol] (Drosophila melanogaster)

FBLIM1 [cytosol] (Gallus gallus)

FBLIM1 [cytosol] (Mus musculus)

FBLIM1 [cytosol] (Rattus norvegicus)

FBLIM1 [cytosol] (Sus scrofa)

FBLIM1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_016857009.1, XP_016857014.1, XP_016857010.1, NP_001019386.1, XP_016857013.1, XP_006710767.1, NP_001019387.1, XP_011539919.1, XP_005245957.1, XP_006710768.1, XP_005245966.1, XP_016857008.1, XP_011539918.1, NP_060026.2, XP_016857012.1, XP_016857011.1, XP_005245959.1, XP_005245960.1, XP_005245958.1

OpenTargets

ENSG00000162458

GeneCards

Q8WUP2

DOCK Blaster

4P3W, 2W0P

PRO

Q8WUP2

Orphanet

25598

PDB

2K9U, 4P3W, 2W0P

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68431 HIST1H3A	59	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) HIST1H3A [extracellular region] (R-HSA-977570) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) AcK19-HIST1H3A [nucleoplasm] (R-HSA-4568761) AcK5-HIST1H3A [nucleoplasm] (R-HSA-4568751) AcK24-HIST1H3A [nucleoplasm] (R-HSA-4568754) AcK15-HIST1H3A [nucleoplasm] (R-HSA-4568743) Ack15-HIST1H3A [nucleoplasm] (R-HSA-4549217) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5229050) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4754188) Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4754169) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791) Me3K80-HIST1H3A [nucleoplasm] (R-HSA-5649795) Me2K80-HIST1H3A [nucleoplasm] (R-HSA-5649768) Me3K37-HIST1H3A [nucleoplasm] (R-HSA-5638160) Me2K37-HIST1H3A [nucleoplasm] (R-HSA-4722125) MeK10-HIST1H3A [nucleoplasm] (R-HSA-212105) MeK28-HIST1H3A [nucleoplasm] (R-HSA-5638327) MeK-10-HIST1H3A [cytosol] (R-HSA-8943830) HIST1H3A [cytosol] (R-HSA-8943829) Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-5244526) MeK5-HIST1H3A [nucleoplasm] (R-HSA-4687016) Cit27-HIST1H3A [nucleoplasm] (R-HSA-5246532) Cit3-HIST1H3A [nucleoplasm] (R-HSA-5246544) Cit9-HIST1H3A [nucleoplasm] (R-HSA-5246530) Cit18-HIST1H3A [nucleoplasm] (R-HSA-5246534) MeR18-HIST1H3A [nucleoplasm] (R-HSA-5229059) MeR3-HIST1H3A [nucleoplasm] (R-HSA-5244529) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5244801) MeR9-HIST1H3A [nucleoplasm] (R-HSA-5244806) Me2K5,Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-8936572) p-T12-HIST1H3A [nucleoplasm] (R-HSA-5625872) p-T12,MeK-10-HIST1H3A [nucleoplasm] (R-HSA-5625859) Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-427734) p-T12, Me2K-10-HIST1H3A [nucleoplasm] (R-HSA-5625790) p-T12, Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-5625757) Me2K10-HIST1H3A [nucleoplasm] (R-HSA-427378) Ack10-HIST1H3A [nucleoplasm] (R-HSA-4568939) Me3K5-HIST1H3A [nucleoplasm] (R-HSA-1214186) HIST1H3A [nucleoplasm] (R-HSA-212070) Me3K-28-HIST1H3A [nucleoplasm] (R-HSA-212220) Me2K5-HIST1H3A [nucleoplasm] (R-HSA-1214170)	0.696	11
UniProt:O60888 CUTA			0.556	3
UniProt:Q8TAP4 LMO3			0.556	3
UniProt:Q6ZSJ9 SHSA6			0.488	2
UniProt:Q5BKX5-3 C19ORF54			0.488	2
UniProt:Q96EY9 ADAT3	1	ADAT3 [nucleoplasm] (R-HSA-6782292)	0.488	2
UniProt:O60888-3 CUTA			0.488	2
UniProt:Q8TAP4-4 LMO3			0.488	2
UniProt:Q6NXT2 H3C			0.488	2
UniProt:Q86UY0 Q86UY0			0.488	2