Reactome | FBLIM1 [cytosol]

FBLIM1 [cytosol]

Stable Identifier

R-HSA-430301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Migfilin

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8WUP2 FBLIM1

Gene Names

FBLIM1, FBLP1

Chain

chain:1-373

Reference Genes

BioGPS Gene:54751 FBLIM1

COSMIC (genes):FBLIM1 FBLIM1

CTD Gene:54751 FBLIM1

dbSNP Gene:54751 FBLIM1

ENSEMBL:ENSG00000162458 FBLIM1

ENSEMBL:ENSG00000162458.13 FBLIM1

HGNC:24686 FBLIM1

KEGG Gene (Homo sapiens):54751 FBLIM1

Monarch:54751 FBLIM1

NCBI Gene:54751 FBLIM1

OMIM:607747 FBLIM1

UCSC:Q8WUP2 FBLIM1

Reference Transcript

Other Identifiers

11718954_a_at

11718955_a_at

11742131_x_at

11747408_x_at

1554795_PM_a_at

1554795_a_at

1555480_PM_a_at

1555480_a_at

1555483_PM_x_at

1555483_x_at

16659746

225258_PM_at

225258_at

2322037

2322038

2322040

2322044

2322046

2322047

2322048

2322049

2322050

2322051

2322052

2322053

2322057

2322060

2322061

2322062

2322063

2322064

44793_s_at

54751

7898263

A_14_P109162

A_23_P23457

A_23_P337934

A_24_P94222

GE56583

GO:0001650

GO:0001725

GO:0005515

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0005856

GO:0005925

GO:0007155

GO:0008092

GO:0008360

GO:0030054

GO:0031005

GO:0033623

GO:0043226

GO:0046872

GO:0048856

GO:0065003

GO:0070161

GO:0071944

GO:0098609

HMNXSV003018404

HMNXSV003038800

HMNXSV003048546

Hs.8728.0.S1_3p_at

Hs2.8728.1.A1_3p_s_at

Hs2.8728.2.A1_3p_a_at

Hs2.8728.2.A1_3p_x_at

ILMN_1691249

ILMN_1799471

ILMN_2353143

PH_hs_0000920

TC01000197.hg

Participates

as a component of

as an input of

Inferred To

ChLim [cytosol] (Dictyostelium discoideum)

Fblim1 [cytosol] (Mus musculus)

Fblim1 [cytosol] (Rattus norvegicus)

Zyx [cytosol] (Drosophila melanogaster)

zyx-1 [cytosol] (Caenorhabditis elegans)

FBLIM1 [cytosol] (Bos taurus)

FBLIM1 [cytosol] (Canis familiaris)

FBLIM1 [cytosol] (Danio rerio)

FBLIM1 [cytosol] (Gallus gallus)

FBLIM1 [cytosol] (Sus scrofa)

FBLIM1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001019387.1, XP_016857014.1, XP_005245957.1, XP_016857010.1, XP_011539919.1, XP_005245960.1, XP_005245958.1, XP_011539918.1, XP_016857008.1, XP_016857013.1, XP_006710767.1, XP_005245959.1, XP_016857011.1, XP_016857009.1, XP_016857012.1, XP_006710768.1, NP_001019386.1, XP_005245966.1, NP_060026.2

OpenTargets

ENSG00000162458

HPA

ENSG00000162458-FBLIM1

GeneCards

Q8WUP2

Ensembl

ENST00000441801, ENST00000332305, ENST00000375771, ENSP00000364926, ENSP00000416387, ENSP00000364920, ENSP00000364921, ENST00000375766, ENSG00000162458

PRO

Q8WUP2

Pharos - Targets

Q8WUP2

Orphanet

25598

PDB

4P3W, 2K9U, 2W0P

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60888 CUTA			0.666	4
UniProt:Q8TAP4 LMO3			0.666	5
UniProt:Q6ZSJ9 SHSA6			0.556	3
UniProt:Q5BKX5-3 ACTMAP			0.556	3
UniProt:Q96EY9 ADAT3	1	ADAT3 [nucleoplasm] (R-HSA-6782292)	0.556	3
UniProt:O60888-3 CUTA			0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:P68431 H3C1	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791)	0.556	3
UniProt:Q6NXT2 H3C			0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	3

Cite Us!