Reactome | FBLIM1 [cytosol]

FBLIM1 [cytosol]

Stable Identifier

R-HSA-430301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Migfilin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WUP2 FBLIM1

Gene Names

FBLIM1, FBLP1

Chain

chain:1-373

Reference Genes

BioGPS Gene:54751 FBLIM1

COSMIC (genes):FBLIM1 FBLIM1

CTD Gene:54751 FBLIM1

dbSNP Gene:54751 FBLIM1

ENSEMBL:ENSG00000162458 FBLIM1

ENSEMBL_homo_sapiens_GENE:ENSG00000162458 FBLIM1

HGNC:24686 FBLIM1

KEGG Gene (Homo sapiens):54751 FBLIM1

Monarch:54751 FBLIM1

NCBI Gene:54751 FBLIM1

OMIM:607747 FBLIM1

UCSC:Q8WUP2 FBLIM1

Reference Transcript

Other Identifiers

0005080273

11718954_a_at

11718955_a_at

11742131_x_at

11747408_x_at

1554795_a_at

1555480_a_at

1555483_x_at

16659746

225258_at

2322037

2322038

2322040

2322044

2322046

2322047

2322048

2322049

2322050

2322051

2322052

2322053

2322057

2322060

2322061

2322062

25287

2K9U

2W0P

44793_s_at

4P3W

54751

72750

7898263

A_14_P109162

A_23_P23457

A_23_P337934

A_24_P94222

AAH19895

AAO15549

AAO49012

BAB55115

BAG51492

CAB61365

CCDS163

CCDS30609

CCDS44064

D6R9I4

D6R9V9

D6RA19

D6RAI6

E7EN81

E7EPI5

E7EWE8

ENSG00000162458

ENSP00000364920

ENSP00000364921

ENSP00000364926

ENSP00000416387

ENST00000332305

ENST00000375766

ENST00000375771

ENST00000441801

EntrezGene:54751

FBLIM1

FBLIM1-201

FBLIM1-202

FBLIM1-203

FBLIM1-206

GE56583

GO:0000902

GO:0001650

GO:0001725

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0005856

GO:0005925

GO:0007155

GO:0008092

GO:0008150

GO:0008360

GO:0022607

GO:0030054

GO:0031005

GO:0033623

GO:0034329

GO:0034330

GO:0043167

GO:0043226

GO:0046872

GO:0048856

GO:0065003

GO:0098609

HGNC:24686

HPA025287

HPA072750

Hs.8728.0.S1_3p_at

Hs2.8728.1.A1_3p_s_at

Hs2.8728.2.A1_3p_a_at

Hs2.8728.2.A1_3p_x_at

ILMN_1671754

ILMN_1691249

ILMN_1799471

ILMN_2353143

IPR001781

MIM:607747

NM_001024215

NM_001024216

NM_001350151

NM_017556

NP_001019386

NP_001019387

NP_001337080

NP_060026

PF00412

PH_hs_0000920

SM00132

TC01000197.hg

uc001axd.2

uc001axe.2

uc001axg.2

uc001axi.2

UPI000013E169

UPI000013F27B

UPI0000520D52

XM_005245900

XM_005245901

XM_005245902

XM_005245903

XM_005245909

XM_006710704

XM_006710705

XM_011541616

XM_011541617

XM_011541618

XM_017001519

XM_017001520

XM_017001521

XM_017001522

XM_017001523

XM_017001524

XM_017001525

XM_017001526

XP_005245957

XP_005245958

XP_005245959

XP_005245960

XP_005245966

XP_006710767

XP_006710768

XP_011539918

XP_011539919

XP_011539920

XP_016857008

XP_016857009

XP_016857010

XP_016857011

XP_016857012

XP_016857013

XP_016857014

XP_016857015

Participant Of

input

hasComponent

Inferred To

Homologues of FBLIM1 [cytosol] (Gallus gallus)

Homologues of FBLIM1 [cytosol] (Rattus norvegicus)

Homologues of FBLIM1 [cytosol] (Sus scrofa)

FBLIM1 [cytosol] (Bos taurus)

FBLIM1 [cytosol] (Canis familiaris)

FBLIM1 [cytosol] (Danio rerio)

FBLIM1 [cytosol] (Gallus gallus)

FBLIM1 [cytosol] (Mus musculus)

FBLIM1 [cytosol] (Rattus norvegicus)

FBLIM1 [cytosol] (Schizosaccharomyces pombe)

FBLIM1 [cytosol] (Sus scrofa)

FBLIM1 [cytosol] (Taeniopygia guttata)

Cross References

RefSeq

XP_006710768.1, XP_016857010.1, XP_016857014.1, XP_016857013.1, XP_016857008.1, XP_011539918.1, XP_006710767.1, NP_001019386.1, XP_005245959.1, XP_005245958.1, XP_016857012.1, NP_060026.2, XP_005245960.1, XP_016857011.1, XP_011539919.1, XP_005245966.1, NP_001019387.1, XP_016857009.1, XP_005245957.1

OpenTargets

ENSG00000162458

GeneCards

Q8WUP2

DOCK Blaster

4P3W, 2W0P

PRO

Q8WUP2

Orphanet

25598

PDB

4P3W, 2K9U, 2W0P

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68431 HIST1H3A	59	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) HIST1H3A [extracellular region] (R-HSA-977570) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) AcK19-HIST1H3A [nucleoplasm] (R-HSA-4568761) AcK5-HIST1H3A [nucleoplasm] (R-HSA-4568751) AcK24-HIST1H3A [nucleoplasm] (R-HSA-4568754) AcK15-HIST1H3A [nucleoplasm] (R-HSA-4568743) Ack15-HIST1H3A [nucleoplasm] (R-HSA-4549217) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5229050) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4754188) Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4754169) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791) Me3K80-HIST1H3A [nucleoplasm] (R-HSA-5649795) Me2K80-HIST1H3A [nucleoplasm] (R-HSA-5649768) Me3K37-HIST1H3A [nucleoplasm] (R-HSA-5638160) Me2K37-HIST1H3A [nucleoplasm] (R-HSA-4722125) MeK10-HIST1H3A [nucleoplasm] (R-HSA-212105) MeK28-HIST1H3A [nucleoplasm] (R-HSA-5638327) MeK-10-HIST1H3A [cytosol] (R-HSA-8943830) HIST1H3A [cytosol] (R-HSA-8943829) Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-5244526) MeK5-HIST1H3A [nucleoplasm] (R-HSA-4687016) Cit27-HIST1H3A [nucleoplasm] (R-HSA-5246532) Cit3-HIST1H3A [nucleoplasm] (R-HSA-5246544) Cit9-HIST1H3A [nucleoplasm] (R-HSA-5246530) Cit18-HIST1H3A [nucleoplasm] (R-HSA-5246534) MeR18-HIST1H3A [nucleoplasm] (R-HSA-5229059) MeR3-HIST1H3A [nucleoplasm] (R-HSA-5244529) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5244801) MeR9-HIST1H3A [nucleoplasm] (R-HSA-5244806) Me2K5,Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-8936572) Ack10-HIST1H3A [nucleoplasm] (R-HSA-4568939) p-T12-HIST1H3A [nucleoplasm] (R-HSA-5625872) p-T12,MeK-10-HIST1H3A [nucleoplasm] (R-HSA-5625859) Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-427734) p-T12, Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-5625757) p-T12, Me2K-10-HIST1H3A [nucleoplasm] (R-HSA-5625790) Me2K10-HIST1H3A [nucleoplasm] (R-HSA-427378) Me2K5-HIST1H3A [nucleoplasm] (R-HSA-1214170) Me3K5-HIST1H3A [nucleoplasm] (R-HSA-1214186) HIST1H3A [nucleoplasm] (R-HSA-212070) Me3K-28-HIST1H3A [nucleoplasm] (R-HSA-212220)	0.696	11
UniProt:O60888 CUTA			0.556	3
UniProt:Q8TAP4 LMO3			0.556	3
UniProt:Q6ZSJ9 SHSA6			0.488	2
UniProt:Q5BKX5-3 C19ORF54			0.488	2
UniProt:Q96EY9 ADAT3	1	ADAT3 [nucleoplasm] (R-HSA-6782292)	0.488	2
UniProt:O60888-3 CUTA			0.488	2
UniProt:Q8TAP4-4 LMO3			0.488	2
UniProt:Q6NXT2 H3C			0.488	2
UniProt:Q86UY0 Q86UY0			0.488	2