p-SLP-76:ADAP binds Ena/VASP

Stable Identifier
R-HSA-430201
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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ADAP (FYB) is an adaptor protein containing multiple binding motifs including an enabled protein vasodilator-stimulated phosphoprotein homology domain 1 (EVH1)-binding domain. This domain binds Ena-VASP family proteins that regulate actin dynamics. The Ena-VASP family member EVL is found in regions of dynamic actin polymerization, such as F-actin rich patches and the distal tips of microspikes.
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