p-SLP-76 binds NCK

Stable Identifier
R-HSA-430190
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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p-SLP-76 binds NCK
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SLP-76 interacts with the adaptor protein NCK1. This interaction involved the SH2 domain of NCK1, leaving 3 three SH3 domains free to interact with other proteins, notably PAK1, N-WASP and Sos.
Literature References
PubMed ID Title Journal Year
9846482 Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

Pappu, R, Bubeck Wardenburg, J, Straus, D, Mayer, B, Bu, JY, Chan, AC, Chernoff, J

Immunity 1998
Participants
Input
Output
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as an event of
Orthologous Events
p-SLP-76 binds NCK (Bos taurus)
p-SLP-76 binds NCK (Canis familiaris)
p-SLP-76 binds NCK (Drosophila melanogaster)
p-SLP-76 binds NCK (Mus musculus)
p-SLP-76 binds NCK (Rattus norvegicus)
p-SLP-76 binds NCK (Sus scrofa)
p-SLP-76 binds NCK (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Harper, MT  (2009-11-02)
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Created
Jupe, S  (2009-08-04)
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