p-SLP-76 binds NCK

Stable Identifier
R-HSA-430190
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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SLP-76 interacts with the adaptor protein NCK1. This interaction involved the SH2 domain of NCK1, leaving 3 three SH3 domains free to interact with other proteins, notably PAK1, N-WASP and Sos.

Literature References
PubMed ID Title Journal Year
9846482 Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

Bubeck Wardenburg, J, Pappu, R, Bu, JY, Mayer, B, Chernoff, J, Straus, D, Chan, AC

Immunity 1998
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created