NCK recruits WASP

Stable Identifier
R-HSA-430180
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The second SH3 domain of NCK interacts with the carboxy-terminal SH3 domain of WASP. WASP family proteins bind the Arp2/3 complex, stimulating its ability to nucleate actin filaments and induce filament branching.

Literature References
PubMed ID Title Journal Year
7565724 Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

Rivero-Lezcano, OM, Marcilla, A, Sameshima, JH, Robbins, KC

Mol Cell Biol 1995
Participants
Participant Of
Orthologous Events
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Reviewed
Created