NCK recruits WASP

Stable Identifier
R-HSA-430180
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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NCK recruits WASP
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The second SH3 domain of NCK interacts with the carboxy-terminal SH3 domain of WASP. WASP family proteins bind the Arp2/3 complex, stimulating its ability to nucleate actin filaments and induce filament branching.
Literature References
PubMed ID Title Journal Year
7565724 Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

Robbins, KC, Rivero-Lezcano, OM, Marcilla, A, Sameshima, JH

Mol Cell Biol 1995
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Authored
Akkerman, JW  (2009-06-03)
Reviewed
Harper, MT  (2009-11-02)
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Created
Jupe, S  (2009-08-04)
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