Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CNOT10 [cytosol]
Stable Identifier
R-HSA-429878
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CCR4-NOT transcription complex subunit 10, CNOTA_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
M-decay: degradation of maternal mRNAs by maternally stored factors (Homo sapiens)
BTG4 binds CNOT7 of the CCR4-NOT complex, PABPN1L, and eIF4E of the mRNP (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:deadenylated mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:deadenylated mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
BTG2 binds CCR4-NOT complex (Homo sapiens)
BTG2:CCR4-NOT [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
Deadenylation of mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H9A5 CNOT10
Gene Names
CNOT10
Chain
initiator methionine:, chain:2-744
Reference Genes
BioGPS Gene:25904 CNOT10
COSMIC (genes):CNOT10 CNOT10
CTD Gene:25904 CNOT10
dbSNP Gene:25904 CNOT10
ENSEMBL:ENSG00000182973 CNOT10
ENSEMBL_homo_sapiens_GENE:ENSG00000182973.20 CNOT10
ENSEMBL_homo_sapiens_GENE:ENSG00000291502.1 CNOT10
HGNC:23817 CNOT10
KEGG Gene (Homo sapiens):25904 CNOT10
Monarch:25904 CNOT10
NCBI Gene:25904 CNOT10
OMIM:620508 CNOT10
UCSC:Q9H9A5 CNOT10
Reference Transcript
RefSeq:NM_001256741.1 CNOT10
RefSeq:NM_015442.2 CNOT10
RefSeq:NM_001256742.1 CNOT10
Other Identifiers
11725063_a_at
11752721_a_at
16938667
223219_PM_s_at
223219_s_at
25904
2616022
2616023
2616027
2616028
2616029
2616030
2616031
2616032
2616033
2616034
2616035
2616039
2616040
2616041
2616043
2616044
2616045
2616046
2616047
2616054
2616055
2616057
2616058
2616061
2616063
2616068
2616070
2616071
2616072
45222_at
8078412
A_14_P101583
A_23_P112652
GE56527
GO:0000289
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006402
GO:0006417
GO:0016020
GO:0016071
GO:0017148
GO:0030014
GO:0031047
GO:0043226
HMNXSV003054299
ILMN_2078334
PH_hs_0026005
TC03000162.hg
g12804152_3p_a_at
Participates
as a component of
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
Inferred To
cnot10 [cytosol]
(Danio rerio)
Cnot10 [cytosol]
(Mus musculus)
Cnot10 [cytosol]
(Rattus norvegicus)
Ghost homologue of CNOT10 [cytosol]
(Xenopus tropicalis)
CNOT10 [cytosol]
(Bos taurus)
CNOT10 [cytosol]
(Canis familiaris)
CNOT10 [cytosol]
(Dictyostelium discoideum)
CNOT10 [cytosol]
(Gallus gallus)
CNOT10 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001243671.1
,
NP_056257.1
,
NP_001243670.1
OpenTargets
ENSG00000182973
HPA
ENSG00000182973-CNOT10
GeneCards
Q9H9A5
Ensembl
ENST00000331889
,
ENST00000328834
,
ENSP00000330060
,
ENSP00000399862
,
ENSG00000182973
,
ENST00000454516
,
ENSP00000329376
PRO
Q9H9A5
Pharos - Targets
Q9H9A5
PDB
8FY3
,
8BFI
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
4
UniProt:P47756 CAPZB
1
CAPZB [cytosol]
(R-HSA-879409)
0.527
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text