Reactome | CNOT10 [cytosol]

CNOT10 [cytosol]

Stable Identifier

R-HSA-429878

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

CCR4-NOT transcription complex subunit 10, CNOTA_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
        
        TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
        
        BTG2 binds CCR4-NOT complex (Homo sapiens)
        
        BTG2:CCR4-NOT [cytosol] (Homo sapiens)
        
        CCR4-NOT Complex [cytosol] (Homo sapiens)
        
        CNOT10 [cytosol] (Homo sapiens)
        
        CCR4-NOT Complex [cytosol] (Homo sapiens)
        
        CNOT10 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H9A5 CNOT10

Gene Names

CNOT10

Chain

initiator methionine:1, chain:2-744

Reference Genes

BioGPS Gene:25904 Q9H9A53

COSMIC (genes):CNOT10 CNOT10

CTD Gene:25904 Q9H9A53

dbSNP Gene:25904 CNOT10

ENSEMBL:ENSG00000182973 CNOT10

HGNC:23817 Q9H9A53

KEGG:hsa:25904 Q9H9A53

Monarch:25904 Q9H9A53

NCBI Gene:25904 Q9H9A53

OMIM:620508 Q9H9A53

UCSC:Q9H9A5 Q9H9A53

Reference Transcript

Participates

as a component of

Inferred To

cnot10 [cytosol] (Danio rerio)

Cnot10 [cytosol] (Mus musculus)

Cnot10 [cytosol] (Rattus norvegicus)

Ghost homologue of CNOT10 [cytosol] (Xenopus tropicalis)

CNOT10 [cytosol] (Bos taurus)

CNOT10 [cytosol] (Canis familiaris)

CNOT10 [cytosol] (Dictyostelium discoideum)

CNOT10 [cytosol] (Gallus gallus)

CNOT10 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_056257.1, NP_001243670.1, NP_001243671.1

ENSEMBL

ENSP00000329376, ENSG00000182973, ENST00000454516, ENSP00000399862, ENST00000707740, ENST00000707745, ENSP00000330060, ENSG00000291502, ENST00000707741, ENSP00000516965, ENSP00000516964, ENST00000331889, ENSP00000516967, ENST00000328834

OpenTargets

ENSG00000182973

GeneCards

CNOT10

HPA

ENSG00000182973-CNOT10

PRO

Q9H9A5

Pharos - Targets

Q9H9A5

GlyGen

Q9H9A5

PDB

8FY3, 8BFI

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	4
UniProt:P47756 CAPZB	1	CAPZB [cytosol] (R-HSA-879409)	0.643	4