The XRN1 exoribonuclease hydrolyzes decapped mRNA from 5' to 3' and yields ribonucleotides having 5'-monophosphates. In yeast Xrn1 associates with the Lsm1-7 complex.
Song, H, Parker, R
Moore, MJ
Achsel, T, Lührmann, R, Arndt-Jovin, DJ, Ingelfinger, D
Fritz, DT, Wilusz, J, Bergman, N, Wilusz, CJ, Kilpatrick, WJ
Stoecklin, G, Mayo, T, Anderson, P
Houseley, J, Tollervey, D
Garneau, NL, Wilusz, J, Wilusz, CJ
Wormington, M, Wilusz, CJ, Peltz, SW
5'-3' exoribonuclease activity of XRN1 [cytosol]
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