Reactome | CLINT1 [cytosol]

CLINT1 [cytosol]

Stable Identifier

R-HSA-429811

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Clathrin interactor 1, EPN4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14677 CLINT1

Gene Names

CLINT1, ENTH, EPN4, EPNR, KIAA0171

Chain

chain:1-625

Reference Genes

BioGPS Gene:9685 CLINT1

COSMIC (genes):CLINT1 CLINT1

CTD Gene:9685 CLINT1

dbSNP Gene:9685 CLINT1

ENSEMBL:ENSG00000113282 CLINT1

ENSEMBL:ENSG00000113282.14 CLINT1

HGNC:23186 CLINT1

KEGG Gene (Homo sapiens):9685 CLINT1

Monarch:9685 CLINT1

NCBI Gene:9685 CLINT1

OMIM:607265 CLINT1

UCSC:Q14677 CLINT1

Reference Transcript

Other Identifiers

11723953_a_at

11723954_s_at

11723955_a_at

11746066_a_at

17002240

201768_PM_s_at

201768_s_at

201769_PM_at

201769_at

2883610

2883611

2883612

2883613

2883614

2883617

2883618

2883624

2883630

2883636

2883637

2883638

2883639

2883640

2883641

2883642

2883654

2883655

2883656

40128_at

8115524

9685

A_23_P133345

A_24_P12149

D79993_at

GE57310

GO:0005515

GO:0005543

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005794

GO:0005829

GO:0005886

GO:0006897

GO:0008289

GO:0016020

GO:0016192

GO:0030125

GO:0030136

GO:0030276

GO:0031410

GO:0043226

GO:0043231

GO:0045296

GO:0048268

GO:0048471

GO:0065003

HMNXSV003048496

ILMN_1745076

PH_hs_0029181

TC05001989.hg

g13325306_3p_a_at

g7661967_3p_at

Participates

as a component of

Golgi-associated vesicle interacting proteins [cytosol] (Homo sapiens)

as an input of

Recruitment Of Cytoplasmic Proteins To Vesicles (Homo sapiens)

Inferred To

epnA [cytosol] (Dictyostelium discoideum)

CLINT1 [cytosol] (Bos taurus)

CLINT1 [cytosol] (Canis familiaris)

CLINT1 [cytosol] (Danio rerio)

CLINT1 [cytosol] (Gallus gallus)

CLINT1 [cytosol] (Mus musculus)

CLINT1 [cytosol] (Plasmodium falciparum)

CLINT1 [cytosol] (Schizosaccharomyces pombe)

CLINT1 [cytosol] (Sus scrofa)

lqfR [cytosol] (Drosophila melanogaster)

ENT3 [cytosol] (Saccharomyces cerevisiae)

rsd-3 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001182485.1, NP_001182484.1, NP_055481.1

OpenTargets

ENSG00000113282

HPA

ENSG00000113282-CLINT1

GeneCards

Q14677

Ensembl

ENSP00000388340, ENST00000411809, ENSP00000429824, ENSP00000429345, ENST00000530742, ENST00000523094, ENST00000523908, ENSG00000113282, ENSP00000433419

PRO

Q14677

Pharos - Targets

Q14677

PDB

2V8S, 2QY7, 1XGW

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O88384	2	Vti1b [extracellular region] (R-MMU-8862983) Vti1b [platelet alpha granule lumen] (R-MMU-8862964)	0.645	6
UniProt:Q9NSY1 BMP2K			0.626	6
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q8WTR4-3 GDPD5			0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:P22892	5	Ap1g1 [cytoplasmic vesicle membrane] (R-MMU-351194) Ap1g1 [Golgi membrane] (R-MMU-350808) Ap1g1 [lysosomal membrane] (R-MMU-432693) Ap1g1 [trans-Golgi network membrane] (R-MMU-2130340) Ap1g1 [cytosol] (R-MMU-167703)	0.544	10
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [autophagosome membrane] (R-HSA-5683641) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [cytosol] (R-HSA-5205651)	0.525	2
UniProt:Q9H0R8 GABARAPL1	3	GABARAPL1 [autophagosome membrane] (R-HSA-5683637) GABARAPL1(1-117) [cytosol] (R-HSA-5682659) GABARAPL1 [cytosol] (R-HSA-5671757)	0.525	2
UniProt:P63167 DYNLL1	6	DYNLL1 [ciliary tip] (R-HSA-5625335) DYNLL1 [cytosol] (R-HSA-387105) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [cilium] (R-HSA-5624863)	0.508	2
UniProt:P29991-PRO_0000037943			0.508	2
UniProt:Q96FJ2 DYNLL2	4	DYNLL2 [ciliary tip] (R-HSA-5625337) DYNLL2 [cilium] (R-HSA-5624865) DYNLL2 [plasma membrane] (R-HSA-140527) DYNLL2 [cytosol] (R-HSA-2029024)	0.508	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	8

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