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SLC5A2 [plasma membrane]
Stable Identifier
R-HSA-429568
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
SGLT2, Sodium/glucose cotransporter 2, SC5A2_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Cellular hexose transport (Homo sapiens)
SLC5A2 binds gliflozins (Homo sapiens)
SLC5A2 [plasma membrane] (Homo sapiens)
SLC5A2:gliflozins [plasma membrane] (Homo sapiens)
SLC5A2 [plasma membrane] (Homo sapiens)
SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Homo sapiens)
SLC5A2 [plasma membrane] (Homo sapiens)
SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Homo sapiens)
SLC5As, NAGLT1 [plasma membrane] (Homo sapiens)
SLC5A2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P31639 SLC5A2
Gene Names
SLC5A2, SGLT2
Chain
chain:1-672
Reference Genes
BioGPS Gene:6524 SLC5A2
COSMIC (genes):SLC5A2 SLC5A2
CTD Gene:6524 SLC5A2
dbSNP Gene:6524 SLC5A2
ENSEMBL:ENSG00000140675.13 SLC5A2
HGNC:11037 SLC5A2
KEGG Gene (Homo sapiens):6524 SLC5A2
Monarch:6524 SLC5A2
NCBI Gene:6524 SLC5A2
OMIM:182381 SLC5A2
UCSC:P31639 SLC5A2
Reference Transcript
RefSeq:NM_003041.3 SLC5A2
Other Identifiers
0005080100
11754701_a_at
16818374
207771_PM_at
207771_at
3657221
3657222
3657224
3657226
3657227
3657228
3657230
3657231
3657232
3657235
3657237
3657238
3657240
3657242
3657243
41305_at
6524
7995222
A_23_P411277
A_33_P3217495
GE81226
GO:0000017
GO:0003014
GO:0005215
GO:0005362
GO:0005412
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005975
GO:0006811
GO:0006814
GO:0008643
GO:0008645
GO:0015151
GO:0015293
GO:0016020
GO:0016021
GO:0016324
GO:0022857
GO:0035623
GO:0043226
GO:0055056
GO:0055085
GO:0070062
GO:0098708
GO:0098719
HMNXSV003024465
ILMN_1666972
ILMN_2070102
M95549_at
TC16000379.hg
g4507032_3p_at
Participates
as a member of
SLC5As, NAGLT1 [plasma membrane] (Homo sapiens)
as a component of
SLC5A2:gliflozins [plasma membrane] (Homo sapiens)
as an input of
SLC5A2 binds gliflozins (Homo sapiens)
Other forms of this molecule
SLC5A2 N654S [plasma membrane]
SLC5A2 R479G [plasma membrane]
SLC5A2 Q167fs*20 [plasma membrane]
SLC5A2 W440* [plasma membrane]
Inferred To
SLC5A2 [plasma membrane]
(Bos taurus)
SLC5A2 [plasma membrane]
(Canis familiaris)
SLC5A2 [plasma membrane]
(Danio rerio)
SLC5A2 [plasma membrane]
(Sus scrofa)
slc5a2 [plasma membrane]
(Xenopus tropicalis)
Slc5a2 [plasma membrane]
(Mus musculus)
Slc5a2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_003032.1
ZINC - World Drugs
SC5A2_HUMAN
Guide to Pharmacology - Targets
916
OpenTargets
ENSG00000140675
ZINC - FDA approved
SC5A2_HUMAN
ZINC - Substances
SC5A2_HUMAN
ZINC - Biogenic
SC5A2_HUMAN
ZINC target
P31639
PRO
P31639
PDB
7VSI
ZINC - Investigational
SC5A2_HUMAN
ZINC - Metabolites
SC5A2_HUMAN
HPA
ENSG00000140675-SLC5A2
GeneCards
P31639
Ensembl
ENSG00000140675
,
ENSP00000327943
,
ENST00000419665
,
ENSP00000410601
,
ENST00000330498
Pharos - Targets
P31639
Orphanet
15516
ZINC - Predictions - Purchasable
SC5A2_HUMAN
HMDB Protein
HMDBP03274
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