Reactome | SGPP1 [endoplasmic reticulum membrane]

SGPP1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-428673

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

sphingosine-1-phosphate phosphatase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BX95 SGPP1

Gene Names

SGPP1, SPP1

Chain

chain:1-441

Reference Genes

BioGPS Gene:81537 SGPP1

COSMIC (genes):SGPP1 SGPP1

COSMIC (genes):SPP1 SGPP1

CTD Gene:81537 SGPP1

dbSNP Gene:81537 SGPP1

ENSEMBL:ENSG00000126821 SGPP1

HGNC:17720 SGPP1

KEGG:hsa:81537 SGPP1

Monarch:81537 SGPP1

NCBI Gene:81537 SGPP1

OMIM:612826 SGPP1

UCSC:Q9BX95 SGPP1

Reference Transcript

RefSeq:NM_030791.3 SGPP1

Other Identifiers

11721907_at

11721908_at

16793750

221268_PM_s_at

221268_s_at

223391_PM_at

223391_at

3568105

3568107

3568109

3568110

3568111

3568112

3568116

3568119

3568120

3568121

3568122

3568123

3568124

43552_at

7979574

81537

A_23_P347048

GE62012

GO:0003824

GO:0005783

GO:0005789

GO:0005886

GO:0006629

GO:0006665

GO:0006668

GO:0006670

GO:0016020

GO:0016787

GO:0030149

GO:0035621

GO:0042392

GO:0043226

GO:0045616

GO:0045682

GO:0046839

GO:0070780

GO:0097191

GO:0097193

HMNXSV003054293

Hs.24678.0.S2_3p_at

ILMN_1679837

PH_hs_0002172

TC14001209.hg

g13540568_3p_s_at

Participates

as a member of

SGPP [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

Homologues of SGPP1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

Sgpp1 [endoplasmic reticulum membrane] (Mus musculus)

Sgpp1 [endoplasmic reticulum membrane] (Rattus norvegicus)

sppA [endoplasmic reticulum membrane] (Dictyostelium discoideum)

sgpp1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

LCB3 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

YSR3 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

SGPP1 [endoplasmic reticulum membrane] (Bos taurus)

SGPP1 [endoplasmic reticulum membrane] (Canis familiaris)

SGPP1 [endoplasmic reticulum membrane] (Gallus gallus)

SGPP1 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

SGPP1 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

2523

ENSEMBL

ENST00000645915, ENSP00000247225, ENST00000247225, ENSP00000496280

OpenTargets

ENSG00000126821

HPA

ENSG00000126821-SGPP1

PRO

Q9BX95

Pharos - Targets

Q9BX95

GlyGen

Q9BX95

HMDB Protein

HMDBP11951

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2

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