Reactome | Organic anion transporters

Organic anion transporters

Stable Identifier

R-HSA-428643

Type

Pathway

Species

Homo sapiens

ReviewStatus

5/5

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The SLC17 gene family encode proteins which are organic anion transporters. There are three distinct subfamilies within SLC17; vesicular glutamate transporters (VGLUT1-3 encoded by SLC17A7,6 and 8), type I Na+-coupled phosphate co-transporters (encoded by SLC17A1-4) and a proton-coupled sialic acid co-transporter (encoded by SLC17A5) (Reimer RJ and Edwards RH, 2004).

Two members of the SLC5 gene family encode carboxylate transporters, SMCT1 and SMCT2 (Ganapathy V et al, 2008).

Literature References

PubMed ID	Title	Journal	Year
12811560	Organic anion transport is the primary function of the SLC17/type I phosphate transporter family Edwards, RH, Reimer, RJ	Pflugers Arch	2004
18446519	Sodium-coupled monocarboxylate transporters in normal tissues and in cancer Itagaki, S, Ganapathy, V, Gopal, E, Thangaraju, M, Prasad, PD, Miyauchi, S, Martin, PM	AAPS J	2008