Reactome | Organic anion transporters

Organic anion transporters

Stable Identifier

R-HSA-428643

Type

Pathway

Species

Homo sapiens

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this pathway in the Pathway Browser

The SLC17 gene family encode proteins which are organic anion transporters. There are three distinct subfamilies within SLC17; vesicular glutamate transporters (VGLUT1-3 encoded by SLC17A7,6 and 8), type I Na+-coupled phosphate co-transporters (encoded by SLC17A1-4) and a proton-coupled sialic acid co-transporter (encoded by SLC17A5) (Reimer RJ and Edwards RH, 2004).

Two members of the SLC5 gene family encode carboxylate transporters, SMCT1 and SMCT2 (Ganapathy V et al, 2008).

Literature References

PubMed ID	Title	Journal	Year
18446519	Sodium-coupled monocarboxylate transporters in normal tissues and in cancer Itagaki, S, Ganapathy, V, Gopal, E, Thangaraju, M, Prasad, PD, Miyauchi, S, Martin, PM	AAPS J	2008
12811560	Organic anion transport is the primary function of the SLC17/type I phosphate transporter family Edwards, RH, Reimer, RJ	Pflugers Arch	2004