Inactivation of RAC1

Stable Identifier
R-HSA-428522
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Vilse and its human homolog ARHGAP39 bind directly to the intracellular domains of the corresponding ROBO receptors and promote the hydrolysis of GTP bound to RAC1 (Lundstrom et al. 2004, Hu et al. 2005).

Participants
Participates
Catalyst Activity

GTPase activator activity of ROBO1:SLIT2:ARHGAP39 [plasma membrane]

Inferred From
Authored
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