Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
IGF2BP1 [cytosol]
Stable Identifier
R-HSA-428366
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Insulin-like growth factor 2 mRNA-binding protein 1, IF2B1_HUMAN, ZBP1, CRD-BP, VICKZ1
Icon
Locations in the PathwayBrowser for interactor UniProt:O95793 STAU1
Expand all
Metabolism of RNA (Homo sapiens)
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA (Homo sapiens)
IGF2BP1 binds specific RNAs (Homo sapiens)
IGF2BP1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
IGF2BP1 binds MAPK4 mRNA (Homo sapiens)
IGF2BP1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZI8 IGF2BP1
Gene Names
IGF2BP1, CRDBP, VICKZ1, ZBP1
Chain
chain:1-577
Reference Genes
BioGPS Gene:10642 IGF2BP1
COSMIC (genes):IGF2BP1 IGF2BP1
CTD Gene:10642 IGF2BP1
dbSNP Gene:10642 IGF2BP1
ENSEMBL:ENSG00000159217 IGF2BP1
HGNC:28866 IGF2BP1
KEGG Gene (Homo sapiens):10642 IGF2BP1
Monarch:10642 IGF2BP1
NCBI Gene:10642 IGF2BP1
OMIM:608288 IGF2BP1
UCSC:Q9NZI8 IGF2BP1
Reference Transcript
RefSeq:NM_001160423.1 IGF2BP1
RefSeq:NM_006546.3 IGF2BP1
Other Identifiers
10642
11727101_at
11727102_a_at
11727103_at
16835517
21367
223689_at
227377_at
3725518
3725519
3725521
3725526
3725527
3725528
3725531
3725532
3725533
3725534
3725535
3725536
3725537
3725540
3725541
3725543
3725544
3725545
3725546
3725547
3725549
3725551
3725552
3725553
3KRM
61347_at
62273
64757_at
72854_at
8008151
83260_s_at
83983_at
A_14_P122163
A_23_P343954
A_23_P83498
AAF37203
ABB46294
AC091133
AC105030
AF198254
CCDS11543
CCDS54138
DQ227344
ENSG00000159217
ENSP00000290341
ENSP00000389135
ENST00000290341
ENST00000290341.7
ENST00000431824
ENST00000431824.2
EntrezGene:10642
EntrezGene:IGF2BP1
g7141071_3p_at
GE733136
GE80369
GE88227
GO:0003674
GO:0003676
GO:0003723
GO:0003729
GO:0003730
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006403
GO:0006412
GO:0006417
GO:0006810
GO:0006950
GO:0008150
GO:0008283
GO:0009056
GO:0009058
GO:0010494
GO:0010610
GO:0017148
GO:0022013
GO:0030027
GO:0030175
GO:0030424
GO:0030425
GO:0030426
GO:0032991
GO:0034641
GO:0034655
GO:0042035
GO:0042995
GO:0043197
GO:0043226
GO:0043488
GO:0045182
GO:0048027
GO:0048471
GO:0048856
GO:0051028
GO:0070934
GO:0070937
GO:0097150
GO:1990904
HGNC:28866
HPA021367
HPA062273
Hs.24739.0.A1_3p_at
Hs.24739.0.A1_3p_x_at
IGF2BP1
IGF2BP1-201
IGF2BP1-202
ILMN_1733807
IPR000504
IPR004087
IPR004088
IPR012677
IPR034837
IPR034842
IPR035979
IPR036612
MIM:608288
NM_001160423
NM_006546
NP_001153895
NP_006537
PF00013
PF00076
PH_hs_0004851
PH_hs_0039031
SM00322
SM00360
TC17000636.hg
TC17002261.hg
UPI0000117170
UPI0000DA8476
XM_005256955
XM_011524201
XM_017024022
XP_005257012
XP_011522503
XP_016879511
Participant Of
input
IGF2BP1 binds MAPK4 mRNA
IGF2BP1 binds specific RNAs
hasComponent
IGF2BP1:MAPK4 mRNA [cytosol]
IGF2BP1:RNA [cytosol]
Inferred To
Homologues of IGF2BP1 [cytosol] (Plasmodium falciparum)
IGF2BP1 [cytosol] (Bos taurus)
IGF2BP1 [cytosol] (Caenorhabditis elegans)
IGF2BP1 [cytosol] (Canis familiaris)
IGF2BP1 [cytosol] (Danio rerio)
IGF2BP1 [cytosol] (Drosophila melanogaster)
IGF2BP1 [cytosol] (Gallus gallus)
IGF2BP1 [cytosol] (Mus musculus)
IGF2BP1 [cytosol] (Plasmodium falciparum)
IGF2BP1 [cytosol] (Rattus norvegicus)
IGF2BP1 [cytosol] (Sus scrofa)
Cross References
RefSeq
NP_001153895.1
,
NP_006537.3
OpenTargets
ENSG00000159217
GeneCards
Q9NZI8
PRO
Q9NZI8
PDB
3KRM
,
6QEY
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00839 HNRNPU
1
HNRNPU [nucleoplasm]
(R-HSA-71953)
0.577
6
UniProt:P67809 YBX1
2
YBX1 [nucleoplasm]
(R-HSA-72041)
YBX1 [extracellular region]
(R-HSA-9017791)
0.577
7
UniProt:O95793 STAU1
0.537
6
UniProt:Q8VDS3 CBX7
0.499
2
© 2019
Reactome