The prototypical transporters of the SLC15 gene family are PEPT1 and PEPT2, which mediate the uptake of every possible di- and tri-peptide. PEPT1 (PTR1) is expressed mainly in the intestine (Liang R et al, 1995; Saito H et al, 1997) while PEPT2 (PTR2) is expressed in the kidney (Liu W et al, 1995).
Ganapathy, ME, Leibach, FH, Ganapathy, V, Hediger, MA, Liang, R, Ramamoorthy, S, Fei, YJ, Liu, W
Han, H, Leibach, FH, Ganapathy, V, Yang-Feng, TL, Hediger, MA, Liang, R, Ramamoorthy, S, Prasad, PD, Fei, YJ
Mukai, M, Saito, H, Motohashi, H, Inui, K
peptide:proton symporter activity of PEPT cotransporters [plasma membrane]
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