The prototypical transporters of the SLC15 gene family are PEPT1 and PEPT2, which mediate the uptake of every possible di- and tri-peptide. PEPT1 (PTR1) is expressed mainly in the intestine (Liang R et al, 1995; Saito H et al, 1997) while PEPT2 (PTR2) is expressed in the kidney (Liu W et al, 1995).
Liang, R, Fei, YJ, Prasad, PD, Ramamoorthy, S, Han, H, Yang-Feng, TL, Hediger, MA, Ganapathy, V, Leibach, FH
Liu, W, Liang, R, Ramamoorthy, S, Fei, YJ, Ganapathy, ME, Hediger, MA, Ganapathy, V, Leibach, FH
Saito, H, Motohashi, H, Mukai, M, Inui, K
peptide:proton symporter activity of PEPT cotransporters [plasma membrane]
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