Activation of Protein Kinase C novel isoforms

Stable Identifier
R-HSA-425861
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Activation of Protein Kinase C novel isoforms
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Activation of the novel Protein Kinase C (nPKC) isoforms (delta, epsilon, eta and theta) requires binding to the membrane lipid diacylglycerol (DAG). nPKC activation is sensitive to DAG concentration.
Literature References
PubMed ID Title Journal Year
  Protein Kinase C 2nd ed

Dekker, L

  2004
19033211 Lipid activation of protein kinases

Newton, AC

J Lipid Res 2009
9601053 The extended protein kinase C superfamily

Mellor, H, Parker, PJ

Biochem J 1998
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Orthologous Events
Activation of Protein Kinase C novel isoforms (Bos taurus)
Activation of Protein Kinase C novel isoforms (Caenorhabditis elegans)
Activation of Protein Kinase C novel isoforms (Canis familiaris)
Activation of Protein Kinase C novel isoforms (Danio rerio)
Activation of Protein Kinase C novel isoforms (Dictyostelium discoideum)
Activation of Protein Kinase C novel isoforms (Drosophila melanogaster)
Activation of Protein Kinase C novel isoforms (Gallus gallus)
Activation of Protein Kinase C novel isoforms (Mus musculus)
Activation of Protein Kinase C novel isoforms (Rattus norvegicus)
Activation of Protein Kinase C novel isoforms (Saccharomyces cerevisiae)
Activation of Protein Kinase C novel isoforms (Schizosaccharomyces pombe)
Activation of Protein Kinase C novel isoforms (Sus scrofa)
Activation of Protein Kinase C novel isoforms (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-06-08)
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