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SLC4A7 [plasma membrane]
Stable Identifier
R-HSA-425552
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium bicarbonate cotransporter 3, S4A7_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD binds effectors at the plasma membrane (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF binds effectors at the plasma membrane (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOF:GTP:RHOF effectors [plasma membrane] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
RHOH binds effectors at the plasma membrane (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOH:GTP:RHOH effectors [plasma membrane] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Bicarbonate transporters (Homo sapiens)
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Homo sapiens)
SLC4A5,7,9 [plasma membrane] (Homo sapiens)
SLC4A7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6M7 SLC4A7
Gene Names
SLC4A7, BT, NBC2, NBC2B, NBC3, NBCn1, SBC2, SLC4A6
Chain
chain:1-1214
Reference Genes
BioGPS Gene:9497 SLC4A7
COSMIC (genes):SLC4A7 SLC4A7
CTD Gene:9497 SLC4A7
dbSNP Gene:9497 SLC4A7
ENSEMBL:ENSG00000033867 SLC4A7
HGNC:11033 SLC4A7
KEGG:hsa:9497 SLC4A7
Monarch:9497 SLC4A7
NCBI Gene:9497 SLC4A7
OMIM:603353 SLC4A7
UCSC:Q9Y6M7 SLC4A7
Reference Transcript
RefSeq:NM_001321104.1 SLC4A7
RefSeq:NM_003615.4 SLC4A7
RefSeq:NM_001321108.1 SLC4A7
RefSeq:NM_001321105.1 SLC4A7
RefSeq:NM_001321106.1 SLC4A7
RefSeq:NM_001258380.1 SLC4A7
RefSeq:XM_017007528.1 SLC4A7
RefSeq:NM_001321103.1 SLC4A7
RefSeq:NM_001321107.1 SLC4A7
RefSeq:XM_017007529.1 SLC4A7
RefSeq:NM_001258379.1 SLC4A7
Other Identifiers
11727279_s_at
11747964_a_at
16951756
207603_PM_at
207604_PM_s_at
207604_s_at
209884_PM_s_at
209884_s_at
210286_PM_s_at
210286_s_at
2666902
2666903
2666905
2666906
2666907
2666908
2666911
2666912
2666913
2666914
2666915
2666916
2666918
2666919
2666920
2666921
2666922
2666923
2666924
2666925
2666926
2666927
2666928
2666929
2666930
2666934
2666936
2666938
2666939
2666940
2666941
2666942
2666944
2666945
2666946
2666947
2666949
2666951
2666953
2666956
2666957
2666959
2666961
2666962
2666963
2666969
34936_at
54598_r_at
56632_r_at
69487_at
8085914
9497
A_23_P132468
A_24_P362931
A_24_P368575
GE81310
GO:0005215
GO:0005452
GO:0005515
GO:0005886
GO:0006164
GO:0006221
GO:0006811
GO:0006814
GO:0006820
GO:0008509
GO:0008510
GO:0015075
GO:0015106
GO:0015291
GO:0015293
GO:0015698
GO:0015701
GO:0016020
GO:0016323
GO:0016324
GO:0016328
GO:0032420
GO:0034220
GO:0035725
GO:0042995
GO:0048856
GO:0051453
GO:0055085
GO:0055086
GO:0060117
GO:0071363
GO:0090383
GO:0098656
HMNXSV003022987
ILMN_1808354
ILMN_2200917
PH_hs_0028028
TC03001255.hg
g4507028_3p_a_at
g5051627_3p_a_at
g6650103_3p_a_at
Participates
as a candidate of
RHOQ effectors [cytosol] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
as a member of
SLC4A5,7,9 [plasma membrane] (Homo sapiens)
Inferred To
Slc4a7 [plasma membrane]
(Mus musculus)
Slc4a7 [plasma membrane]
(Rattus norvegicus)
SLC4A7 [plasma membrane]
(Bos taurus)
SLC4A7 [plasma membrane]
(Canis familiaris)
SLC4A7 [plasma membrane]
(Gallus gallus)
SLC4A7 [plasma membrane]
(Sus scrofa)
abts-1 [plasma membrane]
(Caenorhabditis elegans)
Ndae1 [plasma membrane]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
910
OpenTargets
ENSG00000033867
ENSEMBL
ENSP00000414797
,
ENSP00000416368
,
ENST00000446700
,
ENSP00000407382
,
ENST00000440156
,
ENST00000428386
,
ENST00000295736
,
ENSP00000407304
,
ENSP00000409418
,
ENST00000455077
,
ENST00000437179
,
ENST00000438530
,
ENST00000437266
,
ENSP00000406605
,
ENSP00000408323
,
ENSP00000295736
,
ENSP00000394252
,
ENSP00000390394
,
ENST00000457377
,
ENST00000454389
HPA
ENSG00000033867-SLC4A7
PRO
Q9Y6M7
Pharos - Targets
Q9Y6M7
GlyGen
Q9Y6M7
HMDB Protein
HMDBP03231
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.806
6
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.527
4
UniProt:P20309 CHRM3
1
CHRM3 [plasma membrane]
(R-HSA-399994)
0.527
2
UniProt:Q9NZC3 GDE1
1
GDE1 [plasma membrane]
(R-HSA-1498746)
0.527
3
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.483
2
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.483
2
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