Reactome | SLC4A2 [plasma membrane]

SLC4A2 [plasma membrane]

Stable Identifier

R-HSA-425404

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Anion exchange protein 2, B3A2_HUMAN

Locations in the PathwayBrowser

Expand all

Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
    - Bicarbonate transporters (Homo sapiens)
      - SLC4A1,2,3 exchanges HCO3- for Cl- (Homo sapiens)
        
        SLC4A1,2,3 [plasma membrane] (Homo sapiens)
        
        SLC4A2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P04920 SLC4A2

Gene Names

SLC4A2, AE2, EPB3L1, HKB3, MPB3L

Chain

chain:1-1241

Reference Genes

BioGPS Gene:6522 SLC4A2

COSMIC (genes):SLC4A2 SLC4A2

CTD Gene:6522 SLC4A2

dbSNP Gene:6522 SLC4A2

ENSEMBL:ENSG00000164889 SLC4A2

ENSEMBL_homo_sapiens_GENE:ENSG00000164889.15 SLC4A2

HGNC:11028 SLC4A2

KEGG Gene (Homo sapiens):6522 SLC4A2

Monarch:6522 SLC4A2

NCBI Gene:6522 SLC4A2

OMIM:109280 SLC4A2

UCSC:P04920 SLC4A2

Reference Transcript

Other Identifiers

11725464_a_at

11744668_x_at

17053553

202111_PM_at

202111_at

3031828

3031833

3031834

3031835

3031836

3031837

3031838

3031840

3031841

3031842

3031843

3031844

3031845

3031846

3031847

3031848

3031849

3031850

3031851

3031852

3031854

3031856

3031857

3031859

3031861

3031862

3031864

3031865

3031866

3031868

3031870

3031872

3031873

37557_at

6522

8137352

A_14_P132457

A_23_P253389

GE59290

GO:0002376

GO:0005215

GO:0005452

GO:0005886

GO:0005925

GO:0006811

GO:0006820

GO:0007010

GO:0007155

GO:0007283

GO:0008509

GO:0015106

GO:0015291

GO:0015297

GO:0015698

GO:0015701

GO:0016020

GO:0016323

GO:0016324

GO:0019899

GO:0022414

GO:0022853

GO:0022857

GO:0030154

GO:0030316

GO:0032956

GO:0034220

GO:0043377

GO:0045124

GO:0048565

GO:0048856

GO:0051453

GO:0055085

GO:0070175

GO:0097186

GO:0098656

GO:0098660

GO:0140900

GO:1902476

GO:2000565

HMNXSV003054918

ILMN_2078389

PH_hs_0025300

TC07001012.hg

U62531_at

g4507022_3p_at

p28839

Participates

as a member of

SLC4A1,2,3 [plasma membrane] (Homo sapiens)

Inferred To

slc4a2b [plasma membrane] (Danio rerio)

Ae2 [plasma membrane] (Drosophila melanogaster)

slc4a2 [plasma membrane] (Xenopus tropicalis)

SLC4A2 [plasma membrane] (Bos taurus)

SLC4A2 [plasma membrane] (Canis familiaris)

SLC4A2 [plasma membrane] (Gallus gallus)

SLC4A2 [plasma membrane] (Sus scrofa)

Slc4a2 [plasma membrane] (Mus musculus)

Slc4a2 [plasma membrane] (Rattus norvegicus)

abts-4 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001186622.1, NP_003031.3, NP_001186621.1, NP_001186623.1

Guide to Pharmacology - Targets

905

OpenTargets

ENSG00000164889

GeneCards

P04920

HPA

ENSG00000164889-SLC4A2

Ensembl

ENST00000461735, ENST00000413384, ENSG00000164889, ENSP00000419164, ENST00000485713, ENST00000392826, ENSP00000376571, ENSP00000405600, ENSP00000419412

PRO

P04920

Pharos - Targets

P04920

PDB

8JNI, 8GVA, 8GVE, 8GVF, 8GVC, 8GV9, 8JNJ, 8GV8, 8GVH

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