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CLDN7 [cell junction]
Stable Identifier
R-HSA-421241
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cell junction
Synonyms
Claudin-7, CLD7_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Tight junction interactions (Homo sapiens)
Claudins create paired strands through homophilic and heterophilic cis and trans interactions (Homo sapiens)
claudin trans-homodimer [cell junction] (Homo sapiens)
Claudin [cell junction] (Homo sapiens)
CLDN7 [cell junction] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95471 CLDN7
Gene Names
CLDN7, CEPTRL2, CPETRL2
Chain
chain:1-211
Reference Genes
BioGPS Gene:1366 CLDN7
COSMIC (genes):CLDN7 CLDN7
CTD Gene:1366 CLDN7
dbSNP Gene:1366 CLDN7
ENSEMBL:ENSG00000181885 CLDN7
ENSEMBL_homo_sapiens_GENE:ENSG00000181885.18 CLDN7
ENSEMBL_homo_sapiens_GENE:ENSG00000288292.1 CLDN7
HGNC:2049 CLDN7
KEGG Gene (Homo sapiens):1366 CLDN7
Monarch:1366 CLDN7
NCBI Gene:1366 CLDN7
OMIM:609131 CLDN7
UCSC:O95471 CLDN7
Reference Transcript
RefSeq:NM_001185022.1 CLDN7
RefSeq:NM_001307.5 CLDN7
RefSeq:NM_001185023.1 CLDN7
Other Identifiers
11717015_a_at
1366
16840599
202790_PM_at
202790_at
3743552
3743553
3743554
3743555
3743556
3743557
3743559
3743560
3743561
3743562
3743563
3743564
3743565
38482_at
8012126
A_21_P0000099
A_23_P164284
GE62291
GO:0005198
GO:0005515
GO:0005886
GO:0005923
GO:0007155
GO:0007162
GO:0008284
GO:0012501
GO:0016020
GO:0016323
GO:0016327
GO:0016328
GO:0016338
GO:0019904
GO:0031333
GO:0034330
GO:0042802
GO:0043066
GO:0045471
GO:0048870
GO:0050839
GO:0065003
GO:0070161
GO:0070830
GO:2000147
HMNXSV003002811
PH_hs_0014287
TC17001083.hg
g10835007_3p_at
Participates
as a candidate of
Claudin [cell junction] (Homo sapiens)
Other forms of this molecule
CLDN7 [plasma membrane]
Cross References
RefSeq
NP_001171952.1
,
NP_001298.3
,
NP_001171951.1
OpenTargets
ENSG00000181885
HPA
ENSG00000181885-CLDN7
GeneCards
O95471
Ensembl
ENSG00000181885
,
ENST00000397317
,
ENSP00000353475
,
ENSP00000396638
,
ENSP00000500460
,
ENSP00000500298
,
ENST00000672443
,
ENSG00000288292
,
ENST00000672374
,
ENST00000360325
PRO
O95471
Pharos - Targets
O95471
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43561-2 LAT
2
p-5Y-LAT-2 [plasma membrane]
(R-HSA-2396597)
LAT-2 [plasma membrane]
(R-HSA-2396548)
0.556
3
UniProt:O75396 SEC22B
6
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.556
3
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.556
3
UniProt:Q14162 SCARF1
2
SCARF1 [plasma membrane]
(R-HSA-2197636)
SCARF1 [endocytic vesicle membrane]
(R-HSA-2239453)
0.556
3
UniProt:O95406 CNIH1
3
CNIH1 [endoplasmic reticulum membrane]
(R-HSA-5689439)
CNIH1 [ER to Golgi transport vesicle membrane]
(R-HSA-5689776)
CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689778)
0.556
3
UniProt:P24593 IGFBP5
5
IGFBP5 [extracellular region]
(R-HSA-381414)
IGFBP5(21-163) [extracellular region]
(R-HSA-381415)
IGFBP5(164-272) [extracellular region]
(R-HSA-381478)
IGFBP5 [endoplasmic reticulum lumen]
(R-HSA-8956738)
p-IGFBP5 [endoplasmic reticulum lumen]
(R-HSA-8956988)
0.556
3
UniProt:Q9H1C4 UNC93B1
4
UNC93B1 [Golgi membrane]
(R-HSA-1679064)
UNC93B1 [endoplasmic reticulum membrane]
(R-HSA-1678930)
UNC93B1 P345Pfs*103 [endoplasmic reticulum membrane]
(R-HSA-9628866)
UNC93B1 L230Afs*188 [endoplasmic reticulum membrane]
(R-HSA-9628869)
0.556
3
UniProt:P17152 TMEM11
1
TMEM11 [mitochondrial inner membrane]
(R-HSA-8949578)
0.556
3
UniProt:O60883 GPR37L1
1
GPR37L1 [plasma membrane]
(R-HSA-5336178)
0.556
3
UniProt:O15155 BET1
3
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
BET1 [Golgi membrane]
(R-HSA-6807743)
BET1 [transport vesicle]
(R-HSA-6808719)
0.556
3
UniProt:Q15836 VAMP3
6
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.556
3
UniProt:Q9Y5Z9 UBIAD1
1
UBIAD1 [endoplasmic reticulum membrane]
(R-HSA-2980965)
0.556
3
UniProt:Q5QGT7 RTP2
2
RTP2 [endoplasmic reticulum membrane]
(R-HSA-9752982)
RTP2 [plasma membrane]
(R-HSA-8939446)
0.556
3
UniProt:P05090 APOD
1
APOD [extracellular region]
(R-HSA-5216199)
0.556
3
UniProt:P21854 CD72
1
CD72 [plasma membrane]
(R-HSA-198121)
0.556
3
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