Ca impermeable AMPA receptor ligand binding

Stable Identifier
R-HSA-420975
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ca impermeable AMPA receptor ligand binding
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

AMPA receptors bind glutamate, released in the synaptic cleft by the presynaptic cell, in the ligand binding region in the N terminal domain.

Literature References
PubMed ID Title Journal Year
14567697 Channel-opening kinetics of GluR2Q(flip) AMPA receptor: a laser-pulse photolysis study

Li, G, Pei, W, Niu, L

Biochemistry 2003
19144831 Agonist occupancy is essential for forward trafficking of AMPA receptors

Coleman, SK, Möykkynen, T, Jouppila, A, Koskelainen, S, Rivera, C, Korpi, ER, Keinänen, K

J Neurosci 2009
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
Ca impermeable AMPA receptor ligand binding (Bos taurus)
Ca impermeable AMPA receptor ligand binding (Caenorhabditis elegans)
Ca impermeable AMPA receptor ligand binding (Canis familiaris)
Ca impermeable AMPA receptor ligand binding (Danio rerio)
Ca impermeable AMPA receptor ligand binding (Drosophila melanogaster)
Ca impermeable AMPA receptor ligand binding (Gallus gallus)
Ca impermeable AMPA receptor ligand binding (Mus musculus)
Ca impermeable AMPA receptor ligand binding (Rattus norvegicus)
Ca impermeable AMPA receptor ligand binding (Sus scrofa)
Ca impermeable AMPA receptor ligand binding (Xenopus tropicalis)
Authored
Mahajan, SS  (2008-01-14)
Reviewed
Ziff, EB  (2009-05-15)
Created
Mahajan, SS  (2009-05-15)