Ca impermeable AMPA receptor ligand binding

Stable Identifier
R-HSA-420975
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ca impermeable AMPA receptor ligand binding
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
AMPA receptors bind glutamate, released in the synaptic cleft by the presynaptic cell, in the ligand binding region in the N terminal domain.
Literature References
PubMed ID Title Journal Year
19144831 Agonist occupancy is essential for forward trafficking of AMPA receptors

Keinänen, K, Jouppila, A, Koskelainen, S, Coleman, SK, Rivera, C, Korpi, ER, Möykkynen, T

J Neurosci 2009
14567697 Channel-opening kinetics of GluR2Q(flip) AMPA receptor: a laser-pulse photolysis study

Niu, L, Li, G, Pei, W

Biochemistry 2003
Participants
Input
Output
Participates
as an event of
Orthologous Events
Ca impermeable AMPA receptor ligand binding (Bos taurus)
Ca impermeable AMPA receptor ligand binding (Caenorhabditis elegans)
Ca impermeable AMPA receptor ligand binding (Canis familiaris)
Ca impermeable AMPA receptor ligand binding (Drosophila melanogaster)
Ca impermeable AMPA receptor ligand binding (Gallus gallus)
Ca impermeable AMPA receptor ligand binding (Mus musculus)
Ca impermeable AMPA receptor ligand binding (Rattus norvegicus)
Ca impermeable AMPA receptor ligand binding (Sus scrofa)
Authored
Mahajan, SS  (2008-01-14)
Reviewed
Ziff, EB  (2009-05-15)
Created
Mahajan, SS  (2009-05-15)
Cite Us!