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FANCC [cytosol]
Stable Identifier
R-HSA-420801
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Fanconi anemia group C protein, FANCC_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
PKR-mediated signaling (Homo sapiens)
FA core complex:HSP70s binds PKR (Homo sapiens)
FA Core Complex:HSP70s [cytosol] (Homo sapiens)
FA Core Complex [cytosol] (Homo sapiens)
FANCC [cytosol] (Homo sapiens)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
FA Core Complex:HSP70s [cytosol] (Homo sapiens)
FA Core Complex [cytosol] (Homo sapiens)
FANCC [cytosol] (Homo sapiens)
PKR forms a dimer (Homo sapiens)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
FA Core Complex:HSP70s [cytosol] (Homo sapiens)
FA Core Complex [cytosol] (Homo sapiens)
FANCC [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q00597 FANCC
Gene Names
FANCC, FAC, FACC
Chain
chain:1-558
Reference Genes
BioGPS Gene:2176 FANCC
COSMIC (genes):FANCC FANCC
CTD Gene:2176 FANCC
dbSNP Gene:2176 FANCC
ENSEMBL:ENSG00000158169 FANCC
ENSEMBL_homo_sapiens_GENE:ENSG00000158169.14 FANCC
HGNC:3584 FANCC
KEGG Gene (Homo sapiens):2176 FANCC
Monarch:2176 FANCC
NCBI Gene:2176 FANCC
OMIM:613899 FANCC
UCSC:Q00597 FANCC
Reference Transcript
RefSeq:XM_011518365.2 FANCC
RefSeq:NM_001243743.1 FANCC
RefSeq:NM_000136.2 FANCC
Other Identifiers
105376156
11721591_a_at
11721592_a_at
11756738_a_at
160034_s_at
17096054
1982_s_at
205189_PM_s_at
205189_s_at
2176
3215716
3215717
3215718
3215719
3215720
3215721
3215722
3215723
3215724
3215727
3215732
3215733
3215735
3215736
3215741
3215742
3215752
3215753
3215761
3215763
3215764
3215765
3215787
3215789
3215790
3215791
3215800
3215802
35713_at
72202_f_at
8162514
A_23_P32021
GE59932
GO:0000785
GO:0002262
GO:0002376
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006281
GO:0006289
GO:0006974
GO:0007276
GO:0007281
GO:0019430
GO:0022414
GO:0030154
GO:0034599
GO:0036297
GO:0043226
GO:0043240
GO:0048854
GO:0048856
GO:0065003
GO:0097150
GO:0098754
HMNXSV003009246
HMNXSV003015010
HMNXSV003023258
ILMN_1683112
PH_hs_0023250
TC09001361.hg
X66894_s_at
g4557588_3p_a_at
Participates
as a component of
FA Core Complex [cytosol] (Homo sapiens)
Other forms of this molecule
FANCC [nucleoplasm]
Inferred To
Fancc [cytosol]
(Mus musculus)
Fancc [cytosol]
(Rattus norvegicus)
FANCC [cytosol]
(Bos taurus)
FANCC [cytosol]
(Canis familiaris)
FANCC [cytosol]
(Gallus gallus)
FANCC [cytosol]
(Sus scrofa)
fancc [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001230672.1
,
NP_000127.2
,
XP_011516667.1
OpenTargets
ENSG00000158169
HPA
ENSG00000158169-FANCC
GeneCards
Q00597
Ensembl
ENSP00000289081
,
ENSP00000364454
,
ENST00000375305
,
ENST00000289081
,
ENSG00000158169
PRO
Q00597
Pharos - Targets
Q00597
Orphanet
16022
PDB
7KZV
,
7KZS
,
7KZR
,
7KZT
,
7KZP
,
7KZQ
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9HB96 FANCE
2
FANCE [cytosol]
(R-HSA-420786)
FANCE [nucleoplasm]
(R-HSA-419543)
0.783
6
UniProt:O15360 FANCA
2
FANCA [nucleoplasm]
(R-HSA-419541)
FANCA [cytosol]
(R-HSA-420796)
0.678
3
UniProt:Q13813 SPTAN1
6
SPTAN1 [cytosol]
(R-HSA-201601)
SPTAN1(1-1185) [cytosol]
(R-HSA-202944)
SPTAN1(1186-2472) [cytosol]
(R-HSA-202964)
SPTAN1 [tertiary granule lumen]
(R-HSA-6800874)
SPTAN1 [extracellular region]
(R-HSA-6806322)
SPTAN1 [specific granule lumen]
(R-HSA-6799533)
0.589
2
UniProt:P14625 HSP90B1
4
HSP90B1 [endocytic vesicle lumen]
(R-HSA-3221623)
HSP90B1 [extracellular region]
(R-HSA-3221653)
p-HSP90B1 [endoplasmic reticulum lumen]
(R-HSA-8957016)
HSP90B1 [endoplasmic reticulum lumen]
(R-HSA-981545)
0.581
4
UniProt:Q6FHY5 Q6FHY5
0.556
3
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