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CADM1 [plasma membrane]
Stable Identifier
R-HSA-420589
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Necl-2, Cell adhesion molecule 1, CADM1_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Nectin/Necl trans heterodimerization (Homo sapiens)
Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
Necl-1:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
Necl-2:Nectin 3 trans heterodimer interaction (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
Nectin-3:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
Transhomodimerization of Nectin-like (Necl) proteins (Homo sapiens)
Necl-1/Necl-2/Necl-3 homodimer [plasma membrane] (Homo sapiens)
Necl-2 dimer [plasma membrane] (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
Necl-1/Necl-2/Necl-3 trans homodimer [cell junction] (Homo sapiens)
Necl-1/Necl-2/Necl-3 homodimer [plasma membrane] (Homo sapiens)
Necl-2 dimer [plasma membrane] (Homo sapiens)
CADM1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BY67 CADM1
Gene Names
CADM1, IGSF4, IGSF4A, NECL2, SYNCAM, TSLC1
Chain
signal peptide:1-44, chain:45-442
Reference Genes
BioGPS Gene:23705 CADM1
COSMIC (genes):CADM1 CADM1
CTD Gene:23705 CADM1
dbSNP Gene:23705 CADM1
ENSEMBL:ENSG00000182985 CADM1
HGNC:5951 CADM1
KEGG:hsa:23705 CADM1
Monarch:23705 CADM1
NCBI Gene:23705 CADM1
OMIM:605686 CADM1
UCSC:Q9BY67 CADM1
Reference Transcript
RefSeq:NM_001301045.1 CADM1
RefSeq:NM_001301043.1 CADM1
RefSeq:NM_014333.3 CADM1
RefSeq:NM_001098517.1 CADM1
RefSeq:NM_001301044.1 CADM1
Other Identifiers
11728805_a_at
11728806_a_at
11741375_a_at
11754473_a_at
11757557_s_at
11762680_s_at
209030_PM_s_at
209030_s_at
209031_PM_at
209031_at
209032_PM_s_at
209032_s_at
23705
3392327
3392328
3392329
3392330
3392331
3392333
3392334
3392335
3392336
3392337
3392341
3392342
3392343
3392344
3392345
3392346
3392362
3392363
3392364
3392365
3392366
3392370
3392377
3392381
3392382
3392383
3392384
3392386
3392387
3392393
3392394
3392396
3392398
3392399
3392403
3392410
3392415
3392416
3392417
3392419
3392421
3392464
3392465
3392477
3392478
35829_at
37929_at
51987_at
7951807
A_23_P203120
A_24_P227230
A_33_P3211138
A_33_P3421913
A_33_P3745146
GE54903
GE79982
GE83986
GO:0001819
GO:0001889
GO:0002376
GO:0005102
GO:0005515
GO:0005886
GO:0005911
GO:0006915
GO:0007155
GO:0007156
GO:0007157
GO:0007283
GO:0008037
GO:0012501
GO:0014069
GO:0016020
GO:0016323
GO:0022414
GO:0030154
GO:0030165
GO:0030425
GO:0042271
GO:0042803
GO:0043005
GO:0043226
GO:0045202
GO:0045954
GO:0048856
GO:0050839
GO:0051606
GO:0120154
HMNXSV003031139
HMNXSV003058268
Hs.70337.0.S1_3p_a_at
Hs.70337.0.S1_3p_s_at
Hs.70337.0.S3_3p_at
ILMN_1680132
PH_hs_0022714
PH_hs_0038659
TC11002316.hg
g7767238_3p_a_at
Participates
as a component of
Necl-2 dimer [plasma membrane] (Homo sapiens)
Necl-1:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
Nectin-3:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
as an input of
Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)
Necl-2:Nectin 3 trans heterodimer interaction (Homo sapiens)
Inferred To
CADM1 [plasma membrane]
(Bos taurus)
CADM1 [plasma membrane]
(Canis familiaris)
CADM1 [plasma membrane]
(Gallus gallus)
CADM1 [plasma membrane]
(Sus scrofa)
Ghost homologue of CADM1 [plasma membrane]
(Xenopus tropicalis)
cadm1b [plasma membrane]
(Danio rerio)
Cadm1 [plasma membrane]
(Mus musculus)
Cadm1 [plasma membrane]
(Rattus norvegicus)
Cross References
ENSEMBL
ENST00000331581
,
ENSG00000182985
,
ENSP00000439176
,
ENST00000537058
,
ENST00000452722
,
ENSP00000329797
,
ENSP00000395359
,
ENSP00000439817
,
ENST00000542447
OpenTargets
ENSG00000182985
GeneCards
CADM1
HPA
ENSG00000182985-CADM1
PRO
Q9BY67
Pharos - Targets
Q9BY67
PDB
4H5S
,
3BIN
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95727-1 CRTAM
0.655
4
UniProt:P60900 PSMA6
2
PSMA6 [cytosol]
(R-HSA-68734)
PSMA6 [nucleoplasm]
(R-HSA-174314)
0.556
3
UniProt:Q8TCT7 SPPL2B
1
SPPL2B [plasma membrane]
(R-HSA-8863116)
0.527
3
UniProt:P29074 PTPN4
2
PTPN4 [cytosol]
(R-HSA-8877173)
PTPN4 [nucleoplasm]
(R-HSA-9008925)
0.527
2
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