Reactome | MPP1 [plasma membrane]

MPP1 [plasma membrane]

Stable Identifier

R-HSA-420423

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

55 kDa erythrocyte membrane protein, EM55_HUMAN, p55

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q00013 MPP1

Gene Names

MPP1, DXS552E, EMP55

Chain

initiator methionine:, chain:2-466

Reference Genes

BioGPS Gene:4354 MPP1

COSMIC (genes):MPP1 MPP1

CTD Gene:4354 MPP1

dbSNP Gene:4354 MPP1

ENSEMBL:ENSG00000130830 MPP1

HGNC:7219 MPP1

KEGG:hsa:4354 MPP1

Monarch:4354 MPP1

NCBI Gene:4354 MPP1

OMIM:305360 MPP1

UCSC:Q00013 MPP1

Reference Transcript

Other Identifiers

11722558_x_at

11745504_a_at

11746893_a_at

11746894_x_at

11752958_a_at

17115692

202974_PM_at

202974_at

32207_at

4027586

4027587

4027588

4027589

4027590

4027591

4027592

4027593

4027594

4027595

4027596

4027597

4027598

4027599

4027600

4027601

4027602

4027603

4027604

4027605

4027606

4027607

4027608

4027609

4027610

4027611

4027617

4027620

4027621

4027622

4354

8176174

A_23_P171296

A_33_P3247858

GE58289

GO:0003824

GO:0004385

GO:0005102

GO:0005515

GO:0005856

GO:0005886

GO:0005911

GO:0007165

GO:0016020

GO:0016740

GO:0030863

GO:0032420

GO:0034451

GO:0042995

GO:0043226

GO:0046037

GO:0046710

GO:0055086

GO:0090022

GO:1901135

HMNXSV003056743

ILMN_1733675

M64925_at

PH_hs_0025154

TC0X001544.hg

g6006024_3p_at

Participates

as a component of

Outer hair cell stereocilium tip [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENST00000393531, ENST00000369534, ENSG00000130830, ENSP00000400155, ENSP00000377165, ENST00000413259, ENSP00000358547

OpenTargets

ENSG00000130830

GeneCards

MPP1

HPA

ENSG00000130830-MPP1

PRO

Q00013

Pharos - Targets

Q00013

GlyGen

Q00013

PDB

2EV8, 2EJY, 3NEY

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15439 ABCC4	2	ABCC4 [plasma membrane] (R-HSA-1454927) ABCC4 [platelet dense granule membrane] (R-HSA-391972)	0.707	10
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:Q9NRZ7 AGPAT3	2	AGPAT3 [endoplasmic reticulum membrane] (R-HSA-61807) AGPAT3 [Golgi membrane] (R-HSA-8849239)	0.556	3
UniProt:Q8TDN7 ACER1	1	ACER1 [endoplasmic reticulum membrane] (R-HSA-428221)	0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q96CW1 AP2M1	6	AP2M1 [plasma membrane] (R-HSA-167585) AP2M1 [lysosomal membrane] (R-HSA-196144) AP2M1 [cytosol] (R-HSA-182227) AP2M1 [clathrin-coated endocytic vesicle membrane] (R-HSA-2130423) AP2M1 [endolysosome membrane] (R-HSA-6784828) p-T156 AP2M1 [cytosol] (R-HSA-8856805)	0.556	5
UniProt:P06396 GSN	7	GSN [cytosol] (R-HSA-350275) GSN(28-403) [cytosol] (R-HSA-201618) GSN(404-782) [cytosol] (R-HSA-350272) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN [extracellular region] (R-HSA-6806510) GSN [secretory granule lumen] (R-HSA-6801486) GSN(200-270) [extracellular region] (R-HSA-976940)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.527	2
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.499	2

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