Reactome | CGRP1 receptor:CGRP [plasma membrane]

CGRP1 receptor:CGRP [plasma membrane]

Stable Identifier

R-HSA-420236

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Leishmania infection (Homo sapiens)
    - Leishmania parasite growth and survival (Homo sapiens)
      - Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
        
        ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        CGRP1 receptor:CGRP [plasma membrane] (Homo sapiens)

Participants

components

Participant Of

output

CGRP receptor can bind calcitonin gene-related peptides

hasMember

Ligand:GPCR complexes that activate Gs [plasma membrane]

Inferred To

CGRP1 receptor:CGRP [plasma membrane] (Canis familiaris)

CGRP1 receptor:CGRP [plasma membrane] (Danio rerio)

CGRP1 receptor:CGRP [plasma membrane] (Mus musculus)

CGRP1 receptor:CGRP [plasma membrane] (Rattus norvegicus)

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