Glucagon-like peptide 2 (GLP-2) (Drucker DJ 1999) is a 33-aa proglucagon-derived peptide produced by intestinal enteroendocrine cells. GLP-2 stimulates intestinal growth. The effects of GLP-2 are mediated by the GLP2 receptor (Munroe DG et al, 1999), which can couple with G protein alpha s subunit that activates adenylyl cyclase (Koehler JA et al, 2005).
Munroe, DG, Sumner-Smith, M, Kooshesh, F, Gupta, AK, Drucker, DJ, Wang, H, Rizkalla, G, Kamboj, RK, Demchyshyn, L, Crivici, A, McCallum, K, Vyas, TB, Yang, ZJ, Chen, H
Koehler, JA, Drucker, DJ, Yusta, B
Drucker, DJ
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