Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GHRHR [plasma membrane]
Stable Identifier
R-HSA-420079
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Growth hormone-releasing hormone receptor, GHRHR_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
GHRH receptor binds GHRH (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
GHRHR [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02643 GHRHR
Gene Names
GHRHR
Chain
signal peptide:1-22, chain:23-423
Reference Genes
BioGPS Gene:2692 GHRHR
COSMIC (genes):GHRHR GHRHR
CTD Gene:2692 GHRHR
dbSNP Gene:2692 GHRHR
ENSEMBL:ENSG00000106128 GHRHR
HGNC:4266 GHRHR
KEGG:hsa:2692 GHRHR
Monarch:2692 GHRHR
NCBI Gene:2692 GHRHR
OMIM:139191 GHRHR
UCSC:Q02643 GHRHR
Reference Transcript
RefSeq:NM_000823.4 GHRHR
Other Identifiers
1123_at
11735863_a_at
11742326_a_at
11742327_x_at
11753253_a_at
11762895_at
17044877
207825_PM_s_at
207825_s_at
211544_PM_s_at
211544_s_at
211545_PM_at
211545_at
2692
2995604
2995605
2995609
2995610
2995611
2995612
2995613
2995614
2995615
2995616
2995617
2995619
2995620
2995621
2995622
2995623
2995625
2995626
2995627
2995628
2995630
2995631
2995632
2995633
2995634
2995636
2995637
2995638
2995640
2995641
32383_at
32384_g_at
8132130
A_14_P127277
A_14_P135401
A_21_P0005370
A_23_P8497
A_24_P17048
A_33_P3232655
GE480464
GO:0004888
GO:0004930
GO:0005515
GO:0005637
GO:0005640
GO:0005737
GO:0005886
GO:0007166
GO:0007186
GO:0007189
GO:0007595
GO:0008284
GO:0008340
GO:0008528
GO:0009986
GO:0016020
GO:0016363
GO:0016520
GO:0017046
GO:0019838
GO:0021984
GO:0022414
GO:0030141
GO:0030252
GO:0030879
GO:0031410
GO:0032868
GO:0032869
GO:0033143
GO:0040018
GO:0042445
GO:0043226
GO:0043567
GO:0043568
GO:0043627
GO:0046879
GO:0046887
GO:0048469
GO:0048609
GO:0048856
GO:0051246
GO:0051384
GO:0051649
GO:0060089
GO:0060124
GO:0060133
HMNXSV003011828
HMNXSV003025452
ILMN_1714884
ILMN_1740186
ILMN_2275060
L01406_at
PH_hs_0000090
TC07000200.hg
TC07002237.hg
U17579_rna1_at
g13488768_3p_at
g4503996_3p_a_at
p23762
Participates
as an input of
GHRH receptor binds GHRH (Homo sapiens)
as a member of
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
as a component of
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
Inferred To
GHRHR [plasma membrane]
(Bos taurus)
GHRHR [plasma membrane]
(Canis familiaris)
GHRHR [plasma membrane]
(Gallus gallus)
GHRHR [plasma membrane]
(Sus scrofa)
ghrhrl [plasma membrane]
(Danio rerio)
Ghrhr [plasma membrane]
(Mus musculus)
Ghrhr [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_000814.2
ZINC - World Drugs
GHRHR_HUMAN
Guide to Pharmacology - Targets
247
ENSEMBL
ENSG00000106128
,
ENSP00000320180
,
ENST00000326139
OpenTargets
ENSG00000106128
ZINC - FDA approved
GHRHR_HUMAN
ZINC - Substances
GHRHR_HUMAN
ZINC - Biogenic
GHRHR_HUMAN
ZINC target
Q02643
PRO
Q02643
GlyGen
Q02643
PDB
2XDG
,
7CZ5
GeneCards
GHRHR
HPA
ENSG00000106128-GHRHR
Pharos - Targets
Q02643
Orphanet
GHRHR
ZINC - Predictions - Purchasable
GHRHR_HUMAN
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text