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Go!
GHRH [extracellular region]
Stable Identifier
R-HSA-420068
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Somatoliberin, SLIB_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
GHRH receptor binds GHRH (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
GHRH [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01286 GHRH
Gene Names
GHRH, GHRF
Chain
signal peptide:1-20, propeptide:21-31, peptide:32-75, propeptide:78-108
Reference Genes
BioGPS Gene:2691 GHRH
COSMIC (genes):GHRH GHRH
CTD Gene:2691 GHRH
dbSNP Gene:2691 GHRH
ENSEMBL:ENSG00000118702 GHRH
HGNC:4265 GHRH
KEGG:hsa:2691 GHRH
Monarch:2691 GHRH
NCBI Gene:2691 GHRH
OMIM:139190 GHRH
UCSC:P01286 GHRH
Reference Transcript
RefSeq:NM_021081.5 GHRH
RefSeq:XM_011528788.2 GHRH
RefSeq:NM_001184731.2 GHRH
RefSeq:XM_011528784.2 GHRH
Other Identifiers
11732034_at
1390_s_at
16919101
214524_PM_at
214524_at
2691
3904863
3904866
3904867
3904869
3904874
8066189
A_23_P311818
A_33_P3377100
A_33_P3391826
GE533177
GO:0005102
GO:0005179
GO:0005184
GO:0005576
GO:0005615
GO:0007189
GO:0007267
GO:0008284
GO:0016608
GO:0021984
GO:0023052
GO:0030252
GO:0031770
GO:0032094
GO:0032880
GO:0035264
GO:0040018
GO:0043195
GO:0043204
GO:0043568
GO:0046005
GO:0046879
GO:0046887
GO:0048018
GO:0048856
GO:0051428
GO:0060124
GO:0098772
HMNXSV003049804
Hs.37023.0.S1_3p_at
ILMN_1794372
L00137_cds1_at
TC20000825.hg
Participates
as an input of
GHRH receptor binds GHRH (Homo sapiens)
as a member of
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
as a component of
GHRH receptor:GHRH [plasma membrane] (Homo sapiens)
Inferred To
Ghrh [extracellular region]
(Mus musculus)
Ghrh [extracellular region]
(Rattus norvegicus)
ghrh [extracellular region]
(Danio rerio)
GHRH [extracellular region]
(Bos taurus)
GHRH [extracellular region]
(Canis familiaris)
GHRH [extracellular region]
(Gallus gallus)
GHRH [extracellular region]
(Sus scrofa)
Cross References
RefSeq
XP_011527090.1
,
NP_001171660.1
,
NP_066567.1
,
XP_011527086.1
ENSEMBL
ENSP00000362716
,
ENSP00000517674
,
ENST00000373614
,
ENSP00000237527
,
ENST00000237527
,
ENST00000709405
,
ENST00000709406
,
ENSP00000517673
,
ENSG00000291972
,
ENSG00000118702
OpenTargets
ENSG00000118702
GeneCards
GHRH
HPA
ENSG00000118702-GHRH
PRO
P01286
Pharos - Targets
P01286
PDB
7CZ5
,
5BQM
,
7V9M
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