Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Spectrin beta chain [cytosol]
Stable Identifier
R-HSA-420050
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
L1 linked to actin cytoskeleton by ankyrin (Homo sapiens)
L1 dimer:Ankyrin:Spectrin:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
Autophosphorylation of NCAM1 bound Fyn (Homo sapiens)
Fyn:NCAM1:RPTP-alpha [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Dephosphorylation of NCAM1 bound pFyn (Homo sapiens)
Fyn:NCAM1:RPTP-alpha [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Homo sapiens)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Phosphorylation of FAK by Src kinase (Homo sapiens)
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
pFAK (391) bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Recruitment of FAK to NCAM1:Fyn in lipid rafts (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
pFAK (391) bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Recruitment of Grb2 to pFAK:NCAM1 (Homo sapiens)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Multiple phosphorylated FAK bound to NCAM:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
SOS binds Grb2 bound to pFAK:NCAM1 (Homo sapiens)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Grb2:pFAK bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Homo sapiens)
NCAM1 complexed with pFyn-Y420 [plasma membrane] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Homo sapiens)
Spectrin tetramer [cytosol] (Homo sapiens)
SPTA:SPTB [cytosol] (Homo sapiens)
Spectrin beta chain [cytosol] (Homo sapiens)
Participants
members
SPTB [cytosol]
(Homo sapiens)
SPTBN1 [cytosol]
(Homo sapiens)
SPTBN2 [cytosol]
(Homo sapiens)
SPTBN4 [cytosol]
(Homo sapiens)
SPTBN5 [cytosol]
(Homo sapiens)
Participates
as a component of
SPTA:SPTB [cytosol] (Homo sapiens)
Inferred To
Spectrin beta chain [cytosol]
(Bos taurus)
Spectrin beta chain [cytosol]
(Caenorhabditis elegans)
Spectrin beta chain [cytosol]
(Canis familiaris)
Spectrin beta chain [cytosol]
(Dictyostelium discoideum)
Spectrin beta chain [cytosol]
(Drosophila melanogaster)
Spectrin beta chain [cytosol]
(Gallus gallus)
Spectrin beta chain [cytosol]
(Mus musculus)
Spectrin beta chain [cytosol]
(Rattus norvegicus)
Spectrin beta chain [cytosol]
(Sus scrofa)
Spectrin beta chain [cytosol]
(Xenopus tropicalis)
Ghost homologue of Spectrin beta chain [cytosol]
(Danio rerio)
Ghost homologue of Spectrin beta chain [cytosol]
(Saccharomyces cerevisiae)
ain1 [cytosol]
(Schizosaccharomyces pombe)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
