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CDC42BPB [cytosol]
Stable Identifier
R-HSA-419873
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MRCK beta, Serine/threonine-protein kinase MRCK beta, MRCKB_HUMAN, CDC42-binding protein kinase beta
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CDC42BPB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y5S2 CDC42BPB
Gene Names
CDC42BPB, KIAA1124
Chain
chain:1-1711
Reference Genes
BioGPS Gene:9578 CDC42BPB
COSMIC (genes):CDC42BPB CDC42BPB
CTD Gene:9578 CDC42BPB
dbSNP Gene:9578 CDC42BPB
ENSEMBL:ENSG00000198752 CDC42BPB
ENSEMBL:ENSG00000198752.11 CDC42BPB
HGNC:1738 CDC42BPB
KEGG Gene (Homo sapiens):9578 CDC42BPB
Monarch:9578 CDC42BPB
NCBI Gene:9578 CDC42BPB
OMIM:614062 CDC42BPB
UCSC:Q9Y5S2 CDC42BPB
Reference Transcript
RefSeq:NM_006035.3 CDC42BPB
Other Identifiers
11740260_a_at
16796938
217849_PM_s_at
217849_s_at
3580499
3580500
3580501
3580502
3580505
3580507
3580510
3580511
3580512
3580514
3580522
3580523
3580524
3580526
3580528
3580530
3580531
3580532
3580533
3580534
3580536
3580538
3580540
3580542
3580545
3580546
3580548
3580550
3580552
3580554
3580556
3580557
3580560
3580561
3580562
3580563
3580564
3580568
3580570
3580572
3580576
3580579
3580583
3580587
3580602
3580603
3580604
56549_at
7981387
84805_at
9578
A_23_P380766
GE80225
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0006468
GO:0007010
GO:0007163
GO:0007165
GO:0016020
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0018107
GO:0023052
GO:0030027
GO:0030036
GO:0031032
GO:0031252
GO:0031267
GO:0031532
GO:0036211
GO:0042641
GO:0042995
GO:0043226
GO:0044877
GO:0046872
GO:0048870
GO:0070062
GO:0070161
GO:0106310
GO:0110165
GO:0140096
HMNXSV003012690
HMNXSV003026946
ILMN_1689989
PH_hs_0025557
TC14001534.hg
g5174412_3p_a_at
Participates
as a candidate of
RHOQ effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
as a member of
CDC42 effectors [cytosol] (Homo sapiens)
Inferred To
CDC42BPB [cytosol]
(Bos taurus)
CDC42BPB [cytosol]
(Caenorhabditis elegans)
CDC42BPB [cytosol]
(Canis familiaris)
CDC42BPB [cytosol]
(Danio rerio)
CDC42BPB [cytosol]
(Drosophila melanogaster)
CDC42BPB [cytosol]
(Gallus gallus)
CDC42BPB [cytosol]
(Mus musculus)
CDC42BPB [cytosol]
(Rattus norvegicus)
CDC42BPB [cytosol]
(Sus scrofa)
CDC42BPB [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_006026.3
ZINC - World Drugs
MRCKB_HUMAN
Guide to Pharmacology - Targets
1508
OpenTargets
ENSG00000198752
ZINC - FDA approved
MRCKB_HUMAN
ZINC - Substances
MRCKB_HUMAN
ZINC - Biogenic
MRCKB_HUMAN
ZINC target
Q9Y5S2
PRO
Q9Y5S2
PDB
4UAL
,
3QFV
,
5OTE
,
3TKU
,
5OTF
,
4UAK
ZINC - Investigational
MRCKB_HUMAN
HPA
ENSG00000198752-CDC42BPB
GeneCards
Q9Y5S2
Ensembl
ENSG00000198752
,
ENSP00000355237
,
ENST00000361246
Pharos - Targets
Q9Y5S2
ZINC - Predictions - Purchasable
MRCKB_HUMAN
HMDB Protein
HMDBP08486
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q07157 TJP1
5
TJP1 [cell junction]
(R-HSA-8936023)
TJP1 (?-?) [plasma membrane]
(R-HSA-3209844)
TJP1 [plasma membrane]
(R-HSA-3209845)
TJP1 [Golgi-associated vesicle membrane]
(R-HSA-3209843)
TJP1 [cytosol]
(R-HSA-532659)
0.463
3
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