Binding of ATP to P2X receptors

Stable Identifier
R-HSA-419490
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Binding of ATP to P2X receptors
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P2X receptors are a family of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine triphosphate (ATP) (Gicquel et al. 2015). All members of the family are thought to be functionally trimeric.
Literature References
PubMed ID Title Journal Year
10228183 Single channel properties of P2X2 purinoceptors

Ding, S, Sachs, F

J. Gen. Physiol. 1999
12907444 Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis

Vial, C, Pitt, SJ, Roberts, J, Rolf, MG, Mahaut-Smith, MP, Evans, RJ

Blood 2003
Participants
Input
Output
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as an event of
Orthologous Events
Binding of ATP to P2X receptors (Bos taurus)
Binding of ATP to P2X receptors (Canis familiaris)
Binding of ATP to P2X receptors (Danio rerio)
Binding of ATP to P2X receptors (Dictyostelium discoideum)
Binding of ATP to P2X receptors (Gallus gallus)
Binding of ATP to P2X receptors (Mus musculus)
Binding of ATP to P2X receptors (Rattus norvegicus)
Binding of ATP to P2X receptors (Sus scrofa)
Binding of ATP to P2X receptors (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-05-01)
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