Activation of caspase-3

Stable Identifier
R-HSA-418845
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The DCC-caspase activating complex activates caspase-3 through caspase-9.

Literature References
PubMed ID Title Journal Year
12011067 Mediation of the DCC apoptotic signal by DIP13 alpha

Wu, R, Yao, F, Liu, J, Finley RL, Jr, Morgan, M, Chen, YQ, Thorburn, A

J Biol Chem 2002
15573119 Netrin-1 and its receptors in tumorigenesis

Arakawa, H

Nat Rev Cancer 2004
Participants
Participates
Catalyst Activity

cysteine-type endopeptidase activity of DCC:DIP13alpha:Caspase-9 [plasma membrane]

Orthologous Events
Authored
Reviewed
Created
Cite Us!