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KCNMA1 [plasma membrane]
Stable Identifier
R-HSA-418462
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Calcium-activated potassium channel subunit alpha-1, KCMA1_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Nitric oxide stimulates guanylate cyclase (Homo sapiens)
cGMP effects (Homo sapiens)
PKG1 phosphorylates BK channels (Homo sapiens)
BK channel [plasma membrane] (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Ca2+ activated K+ channels (Homo sapiens)
Activation of Ca2+ activated Potassium channels with large conductance (Homo sapiens)
BK channel [plasma membrane] (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
KCNMA1:KCNMB1:LRRC52 transports K+ from the cytosol to the extracellular region (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
KCNMA1:KCNMB1:LRRC52 [plasma membrane] (Homo sapiens)
KCNMA1:KCNMB1 [plasma membrane] (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Acetylcholine inhibits contraction of outer hair cells (Homo sapiens)
KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
KCNMA1:KCNMB1 [plasma membrane] (Homo sapiens)
KCNMA1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12791 KCNMA1
Gene Names
KCNMA1, KCNMA, SLO
Chain
chain:1-1236
Reference Genes
BioGPS Gene:3778 KCNMA1
COSMIC (genes):KCNMA1 KCNMA1
CTD Gene:3778 KCNMA1
dbSNP Gene:3778 KCNMA1
ENSEMBL:ENSG00000156113 KCNMA1
HGNC:6284 KCNMA1
KEGG:hsa:3778 KCNMA1
Monarch:3778 KCNMA1
NCBI Gene:3778 KCNMA1
OMIM:600150 KCNMA1
UCSC:Q12791 KCNMA1
Reference Transcript
RefSeq:NM_001014797.2 KCNMA1
RefSeq:NM_001161353.1 KCNMA1
RefSeq:NM_001271522.1 KCNMA1
RefSeq:NM_001161352.1 KCNMA1
RefSeq:NM_001271518.1 KCNMA1
RefSeq:NM_002247.3 KCNMA1
Other Identifiers
11720280_at
11723908_at
11744702_a_at
11750376_a_at
11755661_a_at
11759671_s_at
16715793
214921_PM_at
214921_at
221583_PM_s_at
221583_s_at
221584_PM_s_at
221584_s_at
228414_PM_at
228414_at
3296034
3296035
3296036
3296037
3296038
3296039
3296041
3296043
3296045
3296047
3296048
3296049
3296051
3296052
3296053
3296054
3296055
3296056
3296057
3296058
3296059
3296060
3296061
3296062
3296063
3296064
3296065
3296067
3296068
3296069
3296070
3296074
3296075
3296076
3296085
3296087
3296088
3296089
3296095
3296096
3296097
3296098
3296099
3296102
3296107
3296108
3296109
3296113
3296117
3296118
3296119
3296120
3296125
3296126
3296133
3296137
3296138
3296139
3296141
3296144
3296145
3296146
3296147
3296148
3296149
3296150
3296152
3296153
3296154
3296156
3296157
3296159
3296161
3296162
3296163
3296164
3296165
3296166
3296167
3296168
3296169
3296170
3296173
3296174
3296176
3296177
3296178
3296179
3296180
3296185
3296186
3296187
3296192
3296193
3296194
3296195
3296201
3296211
3296212
3296227
3296242
3296261
3296262
3296274
3296275
3296276
3296277
3296278
3296279
3296280
3296281
3296282
3296283
3296284
3296285
3296286
3296287
3296313
3296326
36441_at
36442_g_at
3778
40737_at
47574_at
47575_g_at
52051_at
53796_at
7934570
91355_at
A_23_P60727
A_24_P156490
A_24_P61150
A_24_P916196
A_32_P181222
A_32_P192692
A_33_P3413325
GE58924
GE58947
GE628649
GE79808
GO:0001666
GO:0003012
GO:0003013
GO:0003014
GO:0003779
GO:0005215
GO:0005216
GO:0005249
GO:0005267
GO:0005515
GO:0005886
GO:0005901
GO:0006811
GO:0006813
GO:0006970
GO:0008076
GO:0008092
GO:0015269
GO:0016020
GO:0016324
GO:0022839
GO:0030007
GO:0034465
GO:0034702
GO:0042311
GO:0042391
GO:0042802
GO:0043065
GO:0045211
GO:0045794
GO:0046872
GO:0051592
GO:0055085
GO:0060072
GO:0060073
GO:0060083
GO:0071805
GO:0099094
HMNXSV003041003
HMNXSV003050087
Hs.297229.0.S1_3p_at
Hs.4241.0.A1_3p_at
Hs.89463.0.S1_3p_s_at
ILMN_1740508
ILMN_1794282
ILMN_2297765
PH_hs_0000467
PH_hs_0023966
TC10002715.hg
U02632_at
U11717_s_at
U13913_s_at
g7914977_3p_a_at
Participates
as a component of
KCNMA1:KCNMB1 [plasma membrane] (Homo sapiens)
BK channel [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-S1195-KCNMA1 [plasma membrane]
Inferred To
KCNMA1 [plasma membrane]
(Bos taurus)
KCNMA1 [plasma membrane]
(Canis familiaris)
KCNMA1 [plasma membrane]
(Gallus gallus)
KCNMA1 [plasma membrane]
(Mus musculus)
KCNMA1 [plasma membrane]
(Rattus norvegicus)
KCNMA1 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
380
OpenTargets
ENSG00000156113
ENSEMBL
ENSG00000156113
,
ENSP00000492049
,
ENST00000286627
,
ENSP00000474686
,
ENST00000638759
,
ENST00000286628
,
ENSP00000492632
,
ENST00000640969
,
ENSP00000286628
,
ENST00000626620
,
ENSP00000286627
,
ENSP00000485867
,
ENST00000434208
,
ENST00000480683
,
ENSP00000402150
,
ENST00000638575
,
ENSP00000492200
ZINC - Substances
KCMA1_HUMAN
ZINC target
Q12791
PRO
Q12791
PDB
3MT5
,
2K44
,
6V3G
,
8GHF
,
8GHG
,
6ND0
,
6V5A
,
7YO3
,
6V38
,
6V22
,
8Z3S
,
8GH9
,
3NAF
,
6V35
ZINC - Investigational
KCMA1_HUMAN
HPA
ENSG00000156113-KCNMA1
GeneCards
KCNMA1
Pharos - Targets
Q12791
Orphanet
KCNMA1
ZINC - Predictions - Purchasable
KCMA1_HUMAN
HMDB Protein
HMDBP01738
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