Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
DAPK2 [cytosol]
Stable Identifier
R-HSA-418263
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Death-associated protein kinase 2, DAPK2_HUMAN
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)
DAPK binds UNC5B (Homo sapiens)
DAPKs [cytosol] (Homo sapiens)
DAPK2 [cytosol] (Homo sapiens)
Unc5B with death domain:DAPK [cytosol] (Homo sapiens)
DAPKs [cytosol] (Homo sapiens)
DAPK2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIK4 DAPK2
Gene Names
DAPK2
Chain
chain:1-370
Reference Genes
BioGPS Gene:23604 DAPK2
COSMIC (genes):DAPK2 DAPK2
CTD Gene:23604 DAPK2
dbSNP Gene:23604 DAPK2
ENSEMBL:ENSG00000035664 DAPK2
ENSEMBL_homo_sapiens_GENE:ENSG00000035664.11 DAPK2
HGNC:2675 DAPK2
KEGG Gene (Homo sapiens):23604 DAPK2
Monarch:23604 DAPK2
NCBI Gene:23604 DAPK2
OMIM:616567 DAPK2
UCSC:Q9UIK4 DAPK2
Reference Transcript
RefSeq:NM_014326.3 DAPK2
RefSeq:XM_011521416.2 DAPK2
Other Identifiers
11730526_x_at
11730527_a_at
11748604_a_at
206324_PM_s_at
206324_s_at
215184_PM_at
215184_at
23604
34912_at
3628838
3628839
3628840
3628841
3628842
3628843
3628844
3628845
3628850
3628851
3628852
3628853
3628854
3628855
3628856
3628857
3628858
3628859
3628860
3628861
3628862
3628863
3628865
3628866
3628870
3628872
3628876
3628892
3628893
3628907
3628915
7989596
86878_at
A_24_P10233
GE54486
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005516
GO:0005524
GO:0005634
GO:0005737
GO:0005773
GO:0005794
GO:0006468
GO:0006914
GO:0006915
GO:0010506
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0031410
GO:0034423
GO:0035556
GO:0036211
GO:0042802
GO:0042981
GO:0043065
GO:0043226
GO:0043231
GO:0043276
GO:0046777
GO:0048870
GO:0090023
GO:0106310
GO:0140096
GO:2000424
GO:2001242
HMNXSV003031820
HMNXSV003053607
Hs.266662.0.S1_3p_at
ILMN_1791847
PH_hs_0007533
TC15001546.hg
g7657004_3p_s_at
Participates
as a candidate of
DAPKs [cytosol] (Homo sapiens)
Cross References
RefSeq
XP_011519718.1
,
NP_055141.2
ZINC - World Drugs
DAPK2_HUMAN
Guide to Pharmacology - Targets
2003
OpenTargets
ENSG00000035664
ZINC - FDA approved
DAPK2_HUMAN
ZINC - Substances
DAPK2_HUMAN
ZINC target
Q9UIK4
ZINC - Biogenic
DAPK2_HUMAN
PRO
Q9UIK4
PDB
7A6Y
,
1ZWS
,
1Z9X
,
2CKE
,
1WMK
,
7A6R
,
1ZUZ
,
2A2A
,
6PAW
,
2A27
,
1WRZ
ZINC - Investigational
DAPK2_HUMAN
IntEnz
2.7.11.1
GeneCards
Q9UIK4
HPA
ENSG00000035664-DAPK2
Ensembl
ENSP00000261891
,
ENSP00000484390
,
ENSP00000408277
,
ENST00000261891
,
ENSG00000035664
,
ENSP00000453235
,
ENST00000558069
,
ENST00000612884
,
ENST00000457488
Pharos - Targets
Q9UIK4
ZINC - Predictions - Purchasable
DAPK2_HUMAN
HMDB Protein
HMDBP01151
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text