Src bound to beta-arrestin-2 is not activated

Stable Identifier
R-HSA-418200
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Activated PAR1 can induce the formation of signalling complexes with a beta-arrestin scaffold. When beta-arrestin-1 is incorporated this leads to Src and subsequent ERK activation. In contrast, complexes containing beta-arrestin-2 do not lead to Src and ERK activation.

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