Reactome | PARD6A [plasma membrane]

PARD6A [plasma membrane]

Stable Identifier

R-HSA-418187

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Partitioning defective 6 homolog alpha, PAR6A_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NPB6 PARD6A

Gene Names

PARD6A, PAR6A

Chain

chain:1-346

Reference Genes

BioGPS Gene:50855 PARD6A

COSMIC (genes):PARD6A PARD6A

CTD Gene:50855 PARD6A

dbSNP Gene:50855 PARD6A

ENSEMBL:ENSG00000102981 PARD6A

ENSEMBL_homo_sapiens_GENE:ENSG00000102981.10 PARD6A

HGNC:15943 PARD6A

KEGG Gene (Homo sapiens):50855 PARD6A

Monarch:50855 PARD6A

NCBI Gene:50855 PARD6A

OMIM:607484 PARD6A

UCSC:Q9NPB6 PARD6A

Reference Transcript

Other Identifiers

11715230_s_at

16820249

205245_PM_at

205245_at

3665724

3665725

3665728

3665732

3665733

3665734

37444_at

50855

7996647

A_14_P101481

A_23_P140821

GE58744

GO:0001726

GO:0001933

GO:0005515

GO:0005634

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005886

GO:0005923

GO:0005938

GO:0007010

GO:0007049

GO:0007098

GO:0007163

GO:0016020

GO:0016032

GO:0016324

GO:0030742

GO:0031267

GO:0034330

GO:0034451

GO:0036211

GO:0042995

GO:0043226

GO:0045197

GO:0045217

GO:0050714

GO:0051301

GO:0060341

GO:0070160

GO:0070161

GO:0120157

GO:1904781

HMNXSV003003699

ILMN_1654112

ILMN_2323848

PH_hs_0006209

TC16000544.hg

g8394416_3p_at

Participates

as a member of

PAR-6 [plasma membrane] (Homo sapiens)

Other forms of this molecule

PARD6A [cytosol]

PARD6A [cell junction]

p-S345-PARD6A [plasma membrane]

Inferred To

Pard6a [plasma membrane] (Mus musculus)

Pard6a [plasma membrane] (Rattus norvegicus)

pard6a [plasma membrane] (Danio rerio)

PARD6A [plasma membrane] (Bos taurus)

PARD6A [plasma membrane] (Canis familiaris)

PARD6A [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001032358.1, NP_058644.1

OpenTargets

ENSG00000102981

GeneCards

Q9NPB6

HPA

ENSG00000102981-PARD6A

Ensembl

ENST00000458121, ENSG00000102981, ENSP00000219255, ENSP00000392388, ENST00000219255

PRO

Q9NPB6

Pharos - Targets

Q9NPB6

PDB

1WMH

HMDB Protein

HMDBP08500

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41743 PRKCI	3	PRKCI [nucleoplasm] (R-HSA-9021345) PRKCI [cytosol] (R-HSA-58206) PRKCI [plasma membrane] (R-HSA-420005)	0.949	17
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824)	0.906	10
UniProt:P60953 CDC42	3	CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086) CDC42 [cytosol] (R-HSA-442630) CDC42 [plasma membrane] (R-HSA-449545)	0.755	7
UniProt:P63000 RAC1	6	RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) RAC1 [cytosol] (R-HSA-442615) RAC1 [plasma membrane] (R-HSA-351141)	0.508	2