Reactome | P2Y4 receptor can bind to UTP

P2Y4 receptor can bind to UTP

Stable Identifier

R-HSA-417898

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Nucleotide-like (purinergic) receptors (Homo sapiens)
        
        P2Y receptors (Homo sapiens)
        
        P2Y4 receptor can bind to UTP (Homo sapiens)

General

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The P2Y4 receptor (Communi D et al, 1995) is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.

Literature References

PubMed ID	Title	Journal	Year
8537336	Cloning and functional expression of a human uridine nucleotide receptor Communi, D, Pirotton, S, Parmentier, M, Boeynaems, JM	J Biol Chem	1995

Participants

Input

Output

P2RY4:UTP [plasma membrane] (Homo sapiens)

Participant Of

hasEvent

P2Y receptors

Orthologous Events

P2Y4 receptor can bind to UTP (Bos taurus)

P2Y4 receptor can bind to UTP (Gallus gallus)

P2Y4 receptor can bind to UTP (Mus musculus)

P2Y4 receptor can bind to UTP (Rattus norvegicus)

P2Y4 receptor can bind to UTP (Sus scrofa)

P2Y4 receptor can bind to UTP (Xenopus tropicalis)

Authored

Jassal, B (2009-04-14)

Reviewed

D'Eustachio, P (2009-05-29)

Created

Jassal, B (2009-04-14)