Reactome | P2Y13 binds ADP

P2Y13 binds ADP

Stable Identifier

R-HSA-417843

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Nucleotide-like (purinergic) receptors (Homo sapiens)
        
        P2Y receptors (Homo sapiens)
        
        P2Y13 binds ADP (Homo sapiens)

General

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The P2Y13 receptor is closely related to P2Y12 and displays a high affinity for ADP with coupling to Gi (Communi D et al. 2001).

Literature References

PubMed ID	Title	Journal	Year
11546776	Identification of a novel human ADP receptor coupled to G(i) Lannoy, V, Communi, D, Brezillon, S, Parmentier, M, Gonzalez, NS, Detheux, M, Boeynaems, JM	J Biol Chem	2001