Reactome | P2RY11 [plasma membrane]

P2RY11 [plasma membrane]

Stable Identifier

R-HSA-417837

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

P2Y purinoceptor 11, P2Y11_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Leishmania infection (Homo sapiens)
    - Leishmania parasite growth and survival (Homo sapiens)
      - Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
        
        ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        P2RY11 :ATP [plasma membrane] (Homo sapiens)
        
        P2RY11 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96G91 P2RY11

Gene Names

P2RY11

Chain

chain:1-374

Reference Genes

BioGPS Gene:5032 P2RY11

COSMIC (genes):P2RY11 P2RY11

CTD Gene:5032 P2RY11

dbSNP Gene:5032 P2RY11

ENSEMBL:ENSG00000244165 P2RY11

HGNC:8540 P2RY11

KEGG Gene (Homo sapiens):5032 P2RY11

Monarch:5032 P2RY11

NCBI Gene:5032 P2RY11

OMIM:602697 P2RY11

UCSC:Q96G91 P2RY11

Reference Transcript

RefSeq:NM_002566.4 P2RY11

Other Identifiers

0003140113

11728963_a_at

11754955_a_at

214546_s_at

33633_at

3820373

3820374

3820375

5032

A_23_P4696

A_33_P3239759

GE54234

GO:0002376

GO:0002862

GO:0003674

GO:0004930

GO:0005575

GO:0005886

GO:0005887

GO:0006950

GO:0006952

GO:0007165

GO:0007186

GO:0007190

GO:0007200

GO:0008150

GO:0016020

GO:0016021

GO:0019722

GO:0023041

GO:0030594

GO:0035589

GO:0038023

GO:0045031

GO:0071318

HMNXSV003020373

Hs.166168.0.S1_3p_s_at

ILMN_1752226

PH_hs_0031955

Participates

as an input of

P2Y11 receptor can bind to ATP (Homo sapiens)

as a member of

as a component of

P2RY11 :ATP [plasma membrane] (Homo sapiens)

Inferred To

P2RY11 [plasma membrane] (Bos taurus)

P2RY11 [plasma membrane] (Sus scrofa)

p2ry11 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_002557.2

ZINC - World Drugs

P2Y11_HUMAN

Guide to Pharmacology - Targets

327

OpenTargets

ENSG00000244165

ZINC - Substances

P2Y11_HUMAN

ZINC target

Q96G91

ZINC - Biogenic

P2Y11_HUMAN

PRO

Q96G91

GlyGen

Q96G91

PDB

2B6S

ZINC - Metabolites

P2Y11_HUMAN

HPA

ENSG00000244165-P2RY11

GeneCards

Q96G91

Ensembl

ENSG00000244165, ENSP00000323872, ENST00000321826

Pharos - Targets

Q96G91

ZINC - Predictions - Purchasable

P2Y11_HUMAN

Orphanet

22534

HMDB Protein

HMDBP07862

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