P2Y9 receptor can bind to LPA

Stable Identifier
R-HSA-417820
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The human form of the receptor was cloned and sequenced as GPR23 (Janssens R et al, 1997). P2Y9 has been reported to bind lysophosphatidic acid (LPA) as a ligand and elicit numerous effects via multiple G proteins (Lee CW et al, 2007).

Literature References
PubMed ID Title Journal Year
17166850 LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation

Lee, CW, Rivera, R, Dubin, AE, Chun, J

J Biol Chem 2007
9223435 Cloning of a human heptahelical receptor closely related to the P2Y5 receptor

Janssens, R, Boeynaems, JM, Godart, M, Communi, D

Biochem Biophys Res Commun 1997
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