Reactome | PTGDR2 [plasma membrane]

PTGDR2 [plasma membrane]

Stable Identifier

R-HSA-416895

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

DP2 receptor, CRTH2 receptor, Putative G-protein coupled receptor 44, GPR44, GPR44_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y5Y4 PTGDR2

Gene Names

PTGDR2, CRTH2, DL1R, GPR44

Chain

chain:1-395

Reference Genes

BioGPS Gene:11251 PTGDR2

COSMIC (genes):PTGDR2 PTGDR2

CTD Gene:11251 PTGDR2

dbSNP Gene:11251 PTGDR2

ENSEMBL:ENSG00000183134 PTGDR2

HGNC:4502 PTGDR2

KEGG:hsa:11251 PTGDR2

Monarch:11251 PTGDR2

NCBI Gene:11251 PTGDR2

OMIM:604837 PTGDR2

UCSC:Q9Y5Y4 PTGDR2

Reference Transcript

RefSeq:NM_004778.2 PTGDR2

Other Identifiers

11251

11728066_at

11728067_at

16738864

206361_PM_at

206361_at

216464_PM_x_at

216464_x_at

3375042

3375043

3375044

3375045

3375046

34806_at

7948470

A_24_P115932

GE53230

GO:0001785

GO:0002376

GO:0004930

GO:0004956

GO:0004958

GO:0005886

GO:0006935

GO:0006955

GO:0007186

GO:0007193

GO:0007218

GO:0016020

GO:0019722

GO:0042923

GO:0043005

GO:0045745

GO:0060089

GO:2000255

HMNXSV003014061

Hs.299567.1.S1_3p_a_at

ILMN_1703326

PH_hs_0015448

TC11001843.hg

g4758069_3p_at

Participates

as an input of

DP2 receptor can bind PGD2 (Homo sapiens)

as a component of

PTGDR2:PGD2 [plasma membrane] (Homo sapiens)

Inferred To

Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)

Homologues of PTGDR2 [plasma membrane] (Drosophila melanogaster)

npr-16 [plasma membrane] (Caenorhabditis elegans)

npr-26 [plasma membrane] (Caenorhabditis elegans)

Ptgdr2 [plasma membrane] (Mus musculus)

Ptgdr2 [plasma membrane] (Rattus norvegicus)

AstC-R1 [plasma membrane] (Drosophila melanogaster)

GPR1 [plasma membrane] (Gallus gallus)

LOC100005461 [plasma membrane] (Danio rerio)

AstC-R2 [plasma membrane] (Drosophila melanogaster)

npr-23 [plasma membrane] (Caenorhabditis elegans)

PTGDR2 [plasma membrane] (Bos taurus)

PTGDR2 [plasma membrane] (Caenorhabditis elegans)

PTGDR2 [plasma membrane] (Canis familiaris)

Rh7 [plasma membrane] (Drosophila melanogaster)

npr-24 [plasma membrane] (Caenorhabditis elegans)

npr-28 [plasma membrane] (Caenorhabditis elegans)

npr-18 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_004769.2

Guide to Pharmacology - Targets

339

ENSEMBL

ENSP00000332812, ENST00000332539, ENSG00000183134

OpenTargets

ENSG00000183134

ZINC - FDA approved

PD2R2_HUMAN

ZINC - Substances

PD2R2_HUMAN

ZINC target

Q9Y5Y4

PRO

Q9Y5Y4

GlyGen

Q9Y5Y4

PDB

6D27, 6D26, 7M8W

ZINC - Investigational

PD2R2_HUMAN

GeneCards

PTGDR2

HPA

ENSG00000183134-PTGDR2

Pharos - Targets

Q9Y5Y4

ZINC - Predictions - Purchasable

PD2R2_HUMAN

HMDB Protein

HMDBP02504