SEMA6D binds to PLXNA1:TREM2:DAP12

Stable Identifier
R-HSA-416725
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Plexin-A1 is a receptor for the transmembrane semaphorin, Sema6D. Plexin-A1 associates with the triggering receptor expressed on myeloid cells-2 (Trem-2), linking semaphorin-signalling to the immuno-receptor tyrosine-based activation motif (ITAM)-bearing adaptor protein, DAP12.

Literature References
PubMed ID Title Journal Year
16715077 Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis

Takegahara, N, Takamatsu, H, Toyofuku, T, Tsujimura, T, Okuno, T, Yukawa, K, Mizui, M, Yamamoto, M, Prasad, DV, Suzuki, K, Ishii, M, Terai, K, Moriya, M, Nakatsuji, Y, Sakoda, S, Sato, S, Akira, S, Takeda, K, Inui, M, Takai, T, Ikawa, M, Okabe, M, Kumanogoh, A, Kikutani, H

Nat Cell Biol 2006
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