Inactivation of Rho-GTP by p190RhoGAP

Stable Identifier
R-HSA-416559
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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p190RhoGAP complexed with Plexin-B1 stimulates GTP hydrolysis by RhoA. The resulting lower levels of Rho-GTP may account for F-actin depolymerization and cytoskeletal rearrangements.

Literature References
PubMed ID Title Journal Year
16188938 p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling

Barberis, D, Casazza, A, Sordella, R, Corso, S, Artigiani, S, Settleman, J, Comoglio, PM, Tamagnone, L

J Cell Sci 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
GTPase activator activity of SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created