FOXM1 binds PLK1 promoter

Stable Identifier
R-HSA-4088306
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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FOXM1 binds PLK1 promoter
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MuvB complex, consisting of LIN9, LIN37, LIN52, LIN54 and RBBP4, together with MYBL2 (B-MYB), recruits FOXM1 to CHR (cell cycle genes homology regions) motifs in the promoter of PLK1 gene (Sadasivam et al. 2012, Chen et al. 2013).

Literature References
PubMed ID Title Journal Year
22391450 The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression

Duan, S, Sadasivam, S, DeCaprio, JA

Genes Dev. 2012
23109430 The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism

Fischer, M, Chen, X, Stutchbury, B, Sharrocks, AD, Engeland, K, Han, N, Müller, GA, Quaas, M

Mol. Cell. Biol. 2013
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Authored
Orlic-Milacic, M  (2013-08-14)
Reviewed
Bruinsma, W  (2013-08-21)
Created
Orlic-Milacic, M  (2013-08-12)
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