Reactome | ST8SIA5 [Golgi membrane]

ST8SIA5 [Golgi membrane]

Stable Identifier

R-HSA-4086339

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-2,8-sialyltransferase 8E ecNumber2.4.99.-/ecNumber, SIA8E_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues (Homo sapiens)
        
        ST8SIA1-6 [Golgi membrane] (Homo sapiens)
        
        ST8SIA5 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O15466 ST8SIA5

Gene Names

ST8SIA5, SIAT8E

Chain

chain:1-376

Reference Genes

BioGPS Gene:29906 ST8SIA5

COSMIC (genes):ST8SIA5 ST8SIA5

CTD Gene:29906 ST8SIA5

dbSNP Gene:29906 ST8SIA5

ENSEMBL:ENSG00000101638 ST8SIA5

HGNC:17827 ST8SIA5

KEGG:hsa:29906 ST8SIA5

Monarch:29906 ST8SIA5

NCBI Gene:29906 ST8SIA5

OMIM:607162 ST8SIA5

UCSC:O15466 ST8SIA5

Reference Transcript

Other Identifiers

11752522_a_at

11752523_x_at

11755905_a_at

16855015

206258_PM_at

206258_at

217514_PM_at

217514_at

236110_PM_at

236110_at

29906

32942_at

3806445

3806447

3806448

3806450

3806451

3806453

3806454

3806456

3806458

3806460

3806461

3806462

3806463

3806464

3806465

3806468

3806469

3806471

3806472

3806473

3806476

3806480

3806482

3806483

3806484

3806491

3806492

3806493

3806494

3806495

3806496

3806497

3806498

47836_at

8023121

A_23_P379789

A_32_P125639

A_32_P171571

A_32_P62423

GE59564

GE741471

GO:0000139

GO:0003824

GO:0003828

GO:0005515

GO:0005794

GO:0005975

GO:0006486

GO:0006491

GO:0006629

GO:0006688

GO:0008373

GO:0009311

GO:0016020

GO:0016740

GO:0016757

GO:0043226

GO:1901135

HMNXSV003034136

Hs.6996.0.S1_3p_at

Hs.6996.0.S1_3p_x_at

Hs.6996.1.A1_3p_at

ILMN_1735584

PH_hs_0002019

PH_hs_0018458

TC18000485.hg

TC18000486.hg

TC18000916.hg

g9558746_3p_at

p26038

Participates

as a member of

ST8SIA1-6 [Golgi membrane] (Homo sapiens)

Inferred To

ST8SIA5 [Golgi membrane] (Bos taurus)

ST8SIA5 [Golgi membrane] (Canis familiaris)

ST8SIA5 [Golgi membrane] (Gallus gallus)

ST8SIA5 [Golgi membrane] (Sus scrofa)

St8sia5 [Golgi membrane] (Mus musculus)

St8sia5 [Golgi membrane] (Rattus norvegicus)

st8sia5 [Golgi membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001294915.1, NP_037437.2, NP_001294916.1

ENSEMBL

ENSP00000321343, ENSP00000445492, ENST00000315087, ENST00000538168, ENSG00000101638

OpenTargets

ENSG00000101638

GeneCards

ST8SIA5

HPA

ENSG00000101638-ST8SIA5

PRO

O15466

Pharos - Targets

O15466

GlyGen

O15466

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92624 APBP2			0.556	3
UniProt:Q9NZV5 SELN			0.499	2