Reactome | ST8SIA5 [Golgi membrane]

ST8SIA5 [Golgi membrane]

Stable Identifier

R-HSA-4086339

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-2,8-sialyltransferase 8E ecNumber2.4.99.-/ecNumber, SIA8E_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues (Homo sapiens)
        
        ST8SIA1-6 [Golgi membrane] (Homo sapiens)
        
        ST8SIA5 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O15466 ST8SIA5

Gene Names

ST8SIA5, SIAT8E

Chain

chain:1-376

Reference Genes

BioGPS Gene:29906 ST8SIA5

COSMIC (genes):ST8SIA5 ST8SIA5

CTD Gene:29906 ST8SIA5

dbSNP Gene:29906 ST8SIA5

ENSEMBL:ENSG00000101638.14 ST8SIA5

HGNC:17827 ST8SIA5

KEGG Gene (Homo sapiens):29906 ST8SIA5

Monarch:29906 ST8SIA5

NCBI Gene:29906 ST8SIA5

OMIM:607162 ST8SIA5

UCSC:O15466 ST8SIA5

Reference Transcript

Other Identifiers

0003190039

0100770068

11752522_a_at

11752523_x_at

11755905_a_at

16855015

206258_PM_at

206258_at

217514_PM_at

217514_at

236110_PM_at

236110_at

29906

32942_at

3806445

3806447

3806448

3806450

3806451

3806453

3806454

3806456

3806458

3806460

3806461

3806462

3806463

3806465

3806468

3806469

3806473

3806476

3806480

3806491

3806492

3806493

3806494

3806495

3806496

3806497

47836_at

8023121

A_23_P379789

A_32_P125639

A_32_P171571

A_32_P62423

GE59564

GE741471

GO:0000139

GO:0003828

GO:0005515

GO:0005622

GO:0005737

GO:0005794

GO:0005975

GO:0006486

GO:0006491

GO:0006629

GO:0006688

GO:0008373

GO:0009311

GO:0016020

GO:0016021

GO:0016740

GO:0016757

GO:0036211

GO:0043226

GO:0097503

GO:1901135

HMNXSV003034136

Hs.6996.0.S1_3p_at

Hs.6996.0.S1_3p_x_at

Hs.6996.1.A1_3p_at

ILMN_1735584

PH_hs_0002019

PH_hs_0018458

TC18000485.hg

TC18000486.hg

TC18000916.hg

g9558746_3p_at

p26038

Participates

as a member of

ST8SIA1-6 [Golgi membrane] (Homo sapiens)

Inferred To

ST8SIA5 [Golgi membrane] (Bos taurus)

ST8SIA5 [Golgi membrane] (Canis familiaris)

ST8SIA5 [Golgi membrane] (Gallus gallus)

ST8SIA5 [Golgi membrane] (Mus musculus)

ST8SIA5 [Golgi membrane] (Rattus norvegicus)

ST8SIA5 [Golgi membrane] (Sus scrofa)

st8sia5 [Golgi membrane] (Xenopus tropicalis)

siat 8E [Golgi membrane] (Danio rerio)

Cross References

RefSeq

NP_037437.2, NP_001294915.1, NP_001294916.1

OpenTargets

ENSG00000101638

HPA

ENSG00000101638-ST8SIA5

GeneCards

O15466

Ensembl

ENST00000538168, ENSP00000321343, ENSP00000445492, ENST00000315087, ENSG00000101638

PRO

O15466

Pharos - Targets

O15466