Reactome | ST8SIA1 [Golgi membrane]

ST8SIA1 [Golgi membrane]

Stable Identifier

R-HSA-4086283

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase ecNumber2.4.99.8/ecNumber, SIA8A_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues (Homo sapiens)
        
        ST8SIA1-6 [Golgi membrane] (Homo sapiens)
        
        ST8SIA1 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92185 ST8SIA1

Gene Names

ST8SIA1, SIAT8, SIAT8A

Chain

chain:1-356

Reference Genes

BioGPS Gene:6489 ST8SIA1

COSMIC (genes):ST8SIA1 ST8SIA1

CTD Gene:6489 ST8SIA1

dbSNP Gene:6489 ST8SIA1

ENSEMBL:ENSG00000111728 ST8SIA1

HGNC:10869 ST8SIA1

KEGG Gene (Homo sapiens):6489 ST8SIA1

Monarch:6489 ST8SIA1

NCBI Gene:6489 ST8SIA1

OMIM:601123 ST8SIA1

UCSC:Q92185 ST8SIA1

Reference Transcript

Other Identifiers

0006760411

11715292_at

210073_at

3447041

3447042

3447043

3447044

3447045

3447046

3447047

3447056

3447057

3447063

3447075

3447099

3447100

3447101

3447102

3447103

40678_at

6489

7961755

7961757

A_23_P354705

A_33_P3380751

GE60035

GE800081

GO:0000139

GO:0003674

GO:0003828

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0005975

GO:0006464

GO:0006486

GO:0006491

GO:0006629

GO:0006665

GO:0006688

GO:0006950

GO:0008150

GO:0008283

GO:0008284

GO:0008373

GO:0009058

GO:0009311

GO:0016020

GO:0016021

GO:0016740

GO:0016757

GO:0034605

GO:0043226

GO:0097503

ILMN_1664859

ILMN_2048011

PH_hs_0024758

TC12001301.hg

TC12002790.hg

X77922_s_at

g662253_3p_at

Participant Of

hasMember

ST8SIA1-6 [Golgi membrane]

Inferred To

Sial-T2 [Golgi membrane] (Gallus gallus)

ST8SIA1 [Golgi membrane] (Bos taurus)

ST8SIA1 [Golgi membrane] (Canis familiaris)

ST8SIA1 [Golgi membrane] (Sus scrofa)

St8sia1 [Golgi membrane] (Mus musculus)

St8sia1 [Golgi membrane] (Rattus norvegicus)

st8sia1 [Golgi membrane] (Danio rerio)

st8sia1 [Golgi membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001291379.1, NP_003025.1

OpenTargets

ENSG00000111728

GeneCards

Q92185

HPA

ENSG00000111728-ST8SIA1

Ensembl

ENST00000396037, ENST00000261197, ENSP00000379353, ENSP00000261197, ENSG00000111728

PRO

Q92185

HMDB Protein

HMDBP00271

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