Collagen type VII binds integrin alpha2beta1

Stable Identifier
R-HSA-4086216
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
Locations in the PathwayBrowser
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Summation

The NC1 domains of collagen types VII (Chen et al. 1999) and X (Luckman et al. 2003) interact with integrin alpha2beta1.

Literature References
PubMed ID Title Journal Year
10366422 Alpha 2 beta 1 integrin mediates dermal fibroblast attachment to type VII collagen via a 158-amino-acid segment of the NC1 domain

Chen, M, O'Toole, EA, Li, YY, Woodley, DT

Exp. Cell Res. 1999
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
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Collagen type VII binds integrin alpha2beta1 (Mus musculus)
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Collagen type VII binds integrin alpha2beta1 (Xenopus tropicalis)
Authored
Jupe, S  (2012-08-08)
Reviewed
Ricard-Blum, S  (2013-08-13)