IBSP binds collagen type I

Stable Identifier
R-HSA-4086204
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Bone sialoprotein 2 binds collagen type I
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Bone sialoprotein 2 (IBSP) is an anionic phosphorylated glycoprotein expressed almost exclusively in mineralized tissues. It is a potent nucleator of hydroxyapatite formation. The binding of IBSP to collagen is thought to be important for the initiation of bone mineralization and in the adhesion of bone cells to the mineralized matrix (Fujisawa et al. 1995, Tye et al. 2005).

Participants
Participant Of
Inferred From
Authored
Reviewed
Created
Cite Us!