IBSP binds collagen type I

Stable Identifier
R-HSA-4086204
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Bone sialoprotein 2 binds collagen type I
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
IBSP binds collagen type I
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Bone sialoprotein 2 (IBSP) is an anionic phosphorylated glycoprotein expressed almost exclusively in mineralized tissues. It is a potent nucleator of hydroxyapatite formation. The binding of IBSP to collagen is thought to be important for the initiation of bone mineralization and in the adhesion of bone cells to the mineralized matrix (Fujisawa et al. 1995, Tye et al. 2005).
Participants
Input
Output
Participates
as an event of
Inferred From
Ibsp binds collagen type I (Rattus norvegicus)
Authored
Jupe, S  (2012-08-08)
Reviewed
Ricard-Blum, S  (2013-08-13)
Created
Jupe, S  (2013-08-07)
Cite Us!